A second hit might arise because of viral infection. Tumor-initiating viruses often target RB1 for inactivation. What advantage would a virus gain by inactivating RB function in the host cell? Human papillomavirus (HPV) is an example of a virus that inactivates RB and causes tumors. Which cancer is HPV infection most closely associated with? How is HPV able to inactivate RB? (3-4 sentences only)

Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)
8th Edition
ISBN:9781305634350
Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Chapter6: The Lymphatic And Immune Systems
Section: Chapter Questions
Problem 46LE: ____________ is the process through which a tumor supports its growth by creating its own blood...
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  • A second hit might arise because of viral infection.
    1. Tumor-initiating viruses often target RB1 for inactivation. What advantage would a virus gain by inactivating RB function in the host cell?
    2. Human papillomavirus (HPV) is an example of a virus that inactivates RB and causes tumors. Which cancer is HPV infection most closely associated with? How is HPV able to inactivate RB? (3-4 sentences only) (You’ll need to use the internet for this question, so make sure you paraphrase AND cite your sources)
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