A researcher is creating a new treatment protocol for Myelodysplastic Syndrome (MDS), a form of preleukemia. Following the old treatment protocol, 28% of patients with MDS will develop leukemia within 5 years of MDS diagnosis. He believes his new treatment protocol will lead to fewer MDS patients developing leukemia. He takes a random sample of 100 individuals on his new treatment protocol. Of these 100 individuals, 20 develop leukemia within 5 years of MDS diagnosis.
Conduct a hypothesis test at the 10% level to test this claim that his new treatment protocol will lead to fewer MDS patients developing leukemia.
What is the value of the test statistic? Make sure you round your final answer to two decimal places. Hint: When you are calculating your standard error, round to four decimal places to ensure your test statistic is accurate.
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- Polyunsaturated fatty acids in the diet favorably affect several risk factors for cardiovascular disease. The principal dietary polyunsaturated fat is linoleic acid. Suppose we randomly selected twelve adults for our study. We took their blood pressure measurements (systolic blood pressure) at the start and recorded them for each adult. Then we placed required these adults to consume 23g/day of safflower oil which is high in linoleic acid for four weeks. At the end of the four weeks, we took another systolic blood pressure(SBP) measurement. The paired data is provided below: Subject 1 2 3 4 5 6 7 8 9 10 11 12 Baseline SBP 119.67 100.00 123.56 109.89 96.22 133.33 115.78 126.39 122.78 117.44 111.33 92.39 1-month SBP 117.33 98.78 123.83 107.67 95.67 128.89 113.22 121.56 126.33 110.39 107.00 93.06 Use the appropriate nonparametric test at alpha level of 0.05, to test whether the diet heavy in linoleic acid increases systolic blood pressure (SBP).arrow_forwardA clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions of participants reporting a reduction of symptoms between the experimental and placebo groups. Use α = 0.05. What should the researcher’s conclusion be for a 5% significance level? Reject H0because 2.64 ≥ 1.960. We have statistically significant evidence at α = 0.05 to show that there is a difference in the proportions of patients reporting a reduction in symptoms. We reject H0 at the 5% level because 2.64 is greater than 1.96. We do have statistically…arrow_forwardPolyunsaturated fatty acids in the diet favorably affect several risk factors for cardiovascular disease. The principal dietary polyunsaturated fat is linoleic acid. Suppose we randomly selected twelve adults for our study. We took their blood pressure measurements (systolic blood pressure) at the start and recorded them for each adult. Then we placed required these adults to consume 23g/day of safflower oil which is high in linoleic acid for four weeks. At the end of the four weeks, we took another systolic blood pressure(SBP) measurement. The paired data is provided below: Subject 1 2 3 4 5 6 7 8 9 10 11 12 Baseline SBP 119.67 100.00 123.56 109.89 96.22 133.33 115.78 126.39 122.78 117.44 111.33 92.39 1-month SBP 117.33 98.78 123.83 107.67 95.67 128.89 113.22 121.56 126.33 110.39 107.00 93.06 Use the appropriate nonparametric test at alpha level of 0.05, to test whether the diet heavy in linoleic acid increases systolic blood pressure (SBP). Use Steps 0-5arrow_forward
- You are conducting a study to see if the proportion of voters who prefer the Democratic candidate is significantly larger than 50% at a level of significance of a = 0.10. According to your sample, 49 out of 92 potential voters prefer the Democratic candidate.arrow_forwardresearcher suspects that the actual prevalence of generalized anxiety among children and adolescents is higher than the previously reported prevalence of generalized anxiety disorder among children and adolescents. The previously reported prevalence of generalized anxiety disorder among children and adolescents is 3.9%, and the researcher conducts a study to test the accuracy of the previously reported prevalence of generalized anxiety disorder by recruiting 98 children and adolescents from various pediatricians' offices and tests them for generalized anxiety disorder using the DSM-5. The researcher determines that the prevalence of generalized anxiety disorder among the participants of the study is 6.1%. What should the researcher's conclusion be for a 5% significance level? A. We reject H0 at the 5% level because -57.53 is less than -1.96. We do have statistically significant evidence to show the actual prevalence of generalized anxiety disorder among children and adolescents…arrow_forwardester Hollar is vice president for human resources for a large manufacturing company. In recent years, he has noticed an increase in absenteeism that he thinks is related to the general health of the employees. Four years ago, in an attempt to improve the situation, he began a fitness program in which employees exercise during their lunch hour. To evaluate the program, he selected a random sample of eight participants and found the number of days each was absent in the six months before the exercise program began and in the six months following the exercise program. Below are the results. Employee Before After 1 6 5 2 6 2 3 7 1 4 7 3 5 4 3 6 3 6 7 5 3 8 6 7 At the 0.05 significance level, can he conclude that the number of absences has declined? Estimate the p-value. State the decision rule for 0.05 significance level. (Round your answer to 3 decimal places.) Compute the test statistic. (Round your answer to 3 decimal places.)arrow_forward
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