A researcher found that a single point mutation in the genome of the SARS-CoV-2 virus resulted in change in the spike protein with a His residue being replaced by an Asn. This mutation resulted in significantly increased ability for the virus to evade the immune system. Which of the following is the most likely explanation for this? O changing from His to Asn is a very significant change since Asn is not able to form hydrogen bonds that might have been critical for spike protein-antibody interaction O since Asn is commonly glycosylated, the new residue is likely a new glycosylation site which prevents antibody interaction O the His residue was most likely protonated and positively charged while Asn is neutral and the interaction between the spike protein and antibody is likely through a single electrostatic interaction the His residue was likely recognized by TMPRSS2 and its removal prevented destruction by the protease

During Anfinsen's experiments with ribonuclease A, after denaturation of the protein with urea and 2-mercaptoethanol, what was the outcome when both urea and 2-mercaptoethnal were removed from the system? Re-shuffling of disulfide bonds occurred Recovery of activity Recovery of about 1% activity The enzyme remained inactive O000

What is a cost and benefit to denaturing proteins (ie, a pro and a con)?

1. Determine whether each of the following statements describes the primary, secondary, tertiary, or quaternary stucture of a protein. а. Peptide bonds join amino acids in a polypeptide chain. b. Two polypeptide chains are held together by hydrogen bonds. С. Hydrogen bonds form between adjacent segments of the backbone of the same protein to form a "folded fan" structure. 2. List the type of denaturing agent described by the following treatments: a. disrupting the disulfide bonds in hair to straighten it b. baking the proteins in dough to make bread