Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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In people, controlled crosses can't be made, so geneticists must retreat to examining family records with the expectation that educational matings have been made that can be utilized to find strength and recognize autosomal. The specialist follows the historical backdrop of some variation aggregate back through the historical backdrop of the family and draws up a genealogy, or family, utilizing the standard images.
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- One form of the bleeding disorder known as von Willebrand disease is an autosomal recessive disease. A man who is a carrier marries a woman who is also a carrier of the disease. (a) What percentage of their children are likely to have a disease phenotype? (b) What percentage of their children are likely to have a normal phenotype? (c) What percentage of their children are likely to be carriers of the disease?arrow_forwardAssume that attached earlobes are an autosomal recessive trait with 73% penetrance. If one parent is heterozygous (Aa) and the other homozygous recessive (aa) for the attached earlobe gene, what is the probability that their second child will have attached earlobes? O 73% O 36.5% O 50% O 63.5% O 27% O 13.5% O 18.75%arrow_forwardwhat is the probability that a couple (both heterozygous for the same recessive mutation) will have two children with the disease if the couple plans to have four children in total?arrow_forward
- Genetic Inheritance Patterms Retinitis pigmnentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your Mom and one from your Dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. Question below - short answer approach Imagine you are a genetics counselor, and Dirk, Erik's brother, comes in to see you. Based on his parents, what are Dirk's possible genotypes for RP? What advice would you give Dirk about the chances of Dirk's children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities,…arrow_forwardIn autosomal dominant inheritance patterns, the trait is present in every generation. True Falsearrow_forwardThe next four questions are all related to this problem: Polydactyly (PD) is an autosomal dominant trait (polydactyly - P; wildtype - p). Cystic fibrosis (CF) is an autosomal recessive trait (cystic fibrosis - f; wildtype - F). A PD woman, otherwise normal in phenotype, marries a healthy normal man. Their 4 children are: 1) normal, 2) PD, 3) CF, 4) CF + PD. You will walk through a series of steps to answer this question: What is the probability that their 5th child will have at least one of these conditions? Here is the first step: 1. What is the cross? (Hint: You can use the 4 existing children to determine the genotypes of the parents.) O PpFF (female) x ppFF (male) O PoFf (female) x ppft (male) O pof female) x PPFI (male) O PPFF Ifemale) x ppFf (male) 2. What is/are the target genotypes? O pof OP.F. O pott O P.M 3. What is the probability the child will have PD AND cystic fibrosis? Answer to two decimal places (eg. 0.88). 4. What is the probability that their 5th child will have at…arrow_forward
- Niemann Pick Type C disease is a recessive disorder that causes the accumulation of cholesterol and other lipids in lysosomes, ultimately affecting both the liver and the nervous system. Below are the genotypes and phenotypes of offspring of a family with a history of Niemann Pick. 7 NN ( all normal phenotype) 3 Nn (all normal phenotype) 4 nn (1 early onset dementia, 1 mid-life onset dementia, 2 late-onset dementia). From this information, Niemann-Pick disease is an example of: A) variable expressivity B) incomplete dominance C) incomplete penetrance D) variable expressivity and incomplete penetrance E) multiple allelesarrow_forwardGenetic Inheritance Patterms Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your Mom and one from your Dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. Draw a pedigree of Eric's family showing possible genotypes and chances of having RP. Your pedigree must include his parents, Eric, his brother Dirk, and a potential daughter of Eric's. Draws a pedigree that shows the correct genotypes and chances of having retinitis pigmentosa for Eric and his family. D.Focus (United States) a S W 37 F 八 口arrow_forward
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