A boy with Klinefelter syndrome (47,XXY) is born to a mother who is phenotypically normal and a father who has the X-linked skin condition called anhidrotic ectodermal dysplasia. The mother’s skin is completely normal with no signs of the skin abnormality. In contrast, her son has patches of normal skin and patches of abnormal skin. (a) Which parent contributed the abnormal gamete? (b) Using the appropriate genetic terminology, describe the meiotic mistake that occurred. Be sure to indicate in which division the mistake occurred. (c) Using the appropriate genetic terminology, explain the son’s skin phenotype.

Q: How can epistasis explain incomplete penetrance?

A: Penetrance in genetic terms refers to the ratio of individuals that carry a specific allele of a…

Q: Now assume that the pedigree shown in question 1 shows the inheritance of a rare genetic disease.…

A: The mode of inheritance is a pattern of obtaining parentral alleles  or genes to the offsprings. The…

Q: Which parent passes on the Y chromosome to the child?

A: Part or all of the genetic material of an organism in a long DNA molecule is called a chromosome.…

Q: What is incomplete dominance?

A: The genetics is the branch of biology that deals with the study of genes, genetic variation and…

Q: Hemophilia A is transmitted by an X-linked recessive gene.With an affected father, what is the…

A: Answer: Introduction: In X-linked recessive disorders, an affected father has a mutation in a gene…

Q: Hemophilia is another example of a X-linked disease caused when a recessive allele (Xh) is…

A: Hemophilia is a disorder where blood clots do not form normally which leads to excessive bleeding…

Q: What is complete dominance?

A: Complete dominance: usually in maximum cases the diploid organisms carry 2 alleles of a gene. When…

Q: Why is the development of individuals with Klinefelter's and Turner's syndromes relatively normal,…

A: This syndrome occur due to presence of an additional copy of X chromosomes resulting into karyotype…

Q: by what age a person with trisomy 16 can survive?

A: due to nondisjunction of chromosomes in maternal meiosis I stage, there are high chances of more…

Q: A form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal…

A: 50 percent chances.

Q: Duchenne muscular dystrophy, which is inherited in an X-linked recessive pattern, nearly always…

A: Muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass.…

Q: boy with Klinefelter syndrome (47,XXY) is born to a mother who  is  phenotypically  normal  and  a…

A: Klinefelter syndrome is a rare disorder that is caused in males alone. It is due to the presence of…

Q: What genetic criteria distinguish a case of extranuclear inheritance from (a) a case of Mendelian…

A: Extra nuclear inheritance is the type of inheritance pattern in which genetic information which is…

Q: Duchenne muscular dystrophy (DMD), marked by muscular degeneration, results from an X- linked…

A: Duchenne muscular dystrophy is a X- linked inherited disease which is characterized by degeneration…

Q: A man with X-linked color blindness marries a woman with no history of color blindness in her…

A: Genetics is the branch of biology that deals with genetic material like DNA, RNA, inheritance.…

Q: Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of…

A: The probability is 1/4

Q: Could an individual with blood type O (genotype ii) be a legitimate child of parents in which one…

A: The ABO blood group system is present in human beings. There are four blood groups in the system,…

Q: Why doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an…

A: 1) The pattern of inheritance of the pedigree is autosomal recessive. The father (I-1) is…

Q: An X-linked gene in man is for the disorder haemophilia. This is a recessive trait. Given that a…

A: Haemophilia is an X-linked inherited disease. Haemophilia gene is recessive and expressed only when…

Q: If a man has an X-linked recessive disease, can his sons inherit that disease from him? Why or why…

A: The X-linked recessive disease is caused by a mutation in X chromosomes. X and Y are two sex…

Q: a) What is the chromosomal abnormality associated with Fragile-X Syndrome?   b) What is the…

A: Fragile X syndrome is a genetic condition which causes many problems in development.

Q: Chands syndrome is an autosomal recessive condition characterized by very curly hair, underdeveloped…

A: A pedigree is a diagram of family relationships that uses symbols to represent people and lines to…

Q: What is meant by the term diploid? Which cells of the humanbody are diploid, and which cells are…

A: The ploidy term refers to the number of sets of the chromosomes. The euploidy refers to the…

Q: Hemophilia is another example of an X-linked disease caused when a recessive allele (Xh) is…

A: Hemophilia is a bleeding disorder;which shows X linked recessive pattern of inheritance as the…

Q: What is the difference between extrachromosomal and delayed chromosomal inheritance?

A: Usually the genes are the hereditary units of life. The genes are present in the nucleus and from…

Q: Charles has achondroplasia dwarfism (autosomal dominant) but his wife is normal. What is the…

A:

Q: A karyotype shows that a child has Klinefelter syndrome (47,XXY). If the child is also colorblind…

A: Karyotyping is the process of taking photographs of chromosomal pairs to determine the number of…

Q: If a father is unaffected by an X-linked condition and the mother is a carrier, what is the…

A: Genetics is the branch of biology that deals with the study of heredity and variations. Gregor…

Q: What is incomplete penetrance and what causes it?

A: Introduction  Any gene have two alleles pairs viz. Dominant or Recessive. The allele which gets…

Q: Haemophilia is an X-linked recessive disorder. If a woman is a carrier for haemophil. and has a…

A: Hemophilia is basically an inherited bleeding disorder in which the blood doesn't clot properly,…

Q: What is Trisomy test?

A: The chromosomes are the thread like structure that contains hereditary information in the form of…

Q: Can a son be a carrier for an X-linked trait? Explain.

A: The genetic makeup of an offspring is determined by the genetic makeup of both parents; that is, the…

Q: Could a woman who expresses the x-linked color-blind trait have a son with normal vision?

A: BASIC INFORMATION  COLOR BLINDNESS  it is an X - linked recessive trait  in this the eye is not…

Q: If a girl has blood type AB and her mother is also AB, what are the genotype(s) and corresponding…

A: Genetics is a branch of science that deals with the study of genes, heredity, and genetic…

Q: which mode of inheritance does this trait show (autosomal recessive, autosomal dominant, X-linked…

A: The given image is of a pedigree chart. Squares represent males and circles represent females. Black…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: Hemophilia A is caused by a recessive X-linked allele that encodes a defective form of a clotting…

A: Hemophilia is a blood clotting disorder which slows down the process of blood clotting. People who…

Q: Anhidrotic ectodermal dysplasia is an X-linked recessive disorder in humans characterized by small…

A: Anhidrotic ectodermal dysplasia (AED) is a type of immune deficiency observed in the human body. The…

Q: What is the mode of inheritance for the genes controlling maniac and shiny? autosomal dominant for…

A: Mutation  A kind of alteration in the DNA base pairs either by chemical or physical or by some error…

Q: by what age a person with trisomy 17 can survive?

A: Disease:   When an organism’s body system does not work properly or any organ affects by viruses,…

Q: Two brothers have thick hair that grows over their faces and most of their bodies. This human…

A: Excessive hair growth is linked to Ambras syndrome which is also called hypertrichosis. Ambras…

Q: What is 47,XXX Syndrome ?

A: A syndrome is characterized by a collection of medical indications and symptoms that are related to…

Q: The karyotypes shown here depict chromosomal abnormalities. Name the syndromes and if they are male…

A: "Genes" are the fundamental unit of heredity. They store genetic information in the form of DNA,…

Q: Marfan syndrome is an autosomal dominant disorder caused by mutations in the FBN1 gene. It affects…

A: Understanding the basic law of inheritance is very important to understand the genetics of the…

Q: A boy with Klinefelter syndrome (47,XXY) is born to a motherwho is phenotypically normal and a…

A: XX is female and XY is male. Klinefelter syndrome is a condition when the male has one more extra X…

Q: Why is trisomy 21 not lethal?

A: Trisomy 21 an equivalent name for Down syndrome is the most common genetic disorder. It causes both…

Q: by what age a person with trisomy 13 can survive?

A: Trisomy 13 or Patau syndrome occurs when 3 copies of the chromosome-13 are present in each cell of…

Q: by what age a person with trisomy 18 can survive?

A: Trisomy is a rare genetic condition with three extra copies of chromosomes instead of two copies…

Q: A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the…

A: Genes controls the genetic characteristics of an organism. The genes have two alleles that…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.