(a) (b) O (d) (2) If acetyl-CoA were labeled with ¹4℃ at carbonyl group, and then were used as the substrate for the citric acid cycle. Which of the following intermediates would be produced during the first round of the cycle contains the label at the correct position? OH H | | -oc-c-c−CH,-CO2 I I H CO, OH H T O,C-C–C–CH,-CO, I I H CO, OH H II O,C-C–C–CH, CO I T H CO2 OH H `O,C–C–C–CH2-CO I I H CO2 OH H `O,C-C-C-CH2-CO I I H CO,
(a) (b) O (d) (2) If acetyl-CoA were labeled with ¹4℃ at carbonyl group, and then were used as the substrate for the citric acid cycle. Which of the following intermediates would be produced during the first round of the cycle contains the label at the correct position? OH H | | -oc-c-c−CH,-CO2 I I H CO, OH H T O,C-C–C–CH,-CO, I I H CO, OH H II O,C-C–C–CH, CO I T H CO2 OH H `O,C–C–C–CH2-CO I I H CO2 OH H `O,C-C-C-CH2-CO I I H CO,
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
![**Citric Acid Cycle Intermediate Identification**
**Question:**
If acetyl-CoA were labeled with \(^{14}C\) at the carbonyl group, and then were used as the substrate for the citric acid cycle, which of the following intermediates would be produced during the first round of the cycle containing the label at the correct position?
**Options:**
**(a)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \ ^*{\text{C}} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(b)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \ ^*{\text{CH}_2} - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(c)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \text{CH}_2 - \ ^*{\text{CO}_2^{-}} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(d)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \ ^*{\text{C}} - \text{C} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(e)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc62819af-1f81-4d59-bfb3-1ca1702855ed%2Fbd536828-37c1-4604-a069-381ecaec6518%2F2uqov35_processed.png&w=3840&q=75)
Transcribed Image Text:**Citric Acid Cycle Intermediate Identification**
**Question:**
If acetyl-CoA were labeled with \(^{14}C\) at the carbonyl group, and then were used as the substrate for the citric acid cycle, which of the following intermediates would be produced during the first round of the cycle containing the label at the correct position?
**Options:**
**(a)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \ ^*{\text{C}} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(b)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \ ^*{\text{CH}_2} - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(c)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \text{CH}_2 - \ ^*{\text{CO}_2^{-}} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(d)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \ ^*{\text{C}} - \text{C} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(e)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\
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