Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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9. Explain how a small amount of growth factor can mediate an amplified signal inside the cytoplasm of
the cell and lead to the activation of transcription factors in the nucleus
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- 2. A husband and wife both have normal skin pigmentation. Their first child is albino. Give the genotypes of the parents and of the albino child. Give the genotypes of the parents and of the albino child. What is the chance that if they have a second child, this child will not be albino? what is the chance that if they have a third child, this child will be albino? 3. translate the following sequence of messenger RNA nucleotides in a sequence of amino acids forming part of a polypeptide chain a. C-U-G-U-U-U-U-G-C-A-G-U-G-G-U-U b. write the sequence of nucleotides for the portion of a DNA molecule that served as a pattern or template for the formation of the messenger RNA above. c. A certain protein contains the following sequence of amino acids: isoleucine-serine-arginine-glutamic acid-serine-proline-valine-glutamic acid. Using the table found in your text, write the sequence of RNA triplet that would code for this sequence of amino acids. then write the sequence of DNA triplets that…arrow_forward2. Consider the scenario where a DNA mutation occurs in a person's skin cells, where the gene p53 becomes damaged, and can no longer be transcribed and translated into a functioning 53kd protein. Why might a mutation of this nature be especially concerning to someone who experiences regular exposure to skin carcinogens, such as UV light? ✓✓✓arrow_forward6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis. Ferritin A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein? B. How is activity of the IRE binding protein regulated? C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain. Explanation Transferrin receptor RNA levels ( ) high ( ) low ( ) high ( ) low Protein levels () high levels ( ) low levels () high levels ( ) low levelsarrow_forward
- 2arrow_forward2. Which of the following is a true statement concerning condons? Condon specifies one amino acid is found in all eukaryotes, but not in prokaryotes will be read by RNA polymerase during transcription is composed of two nucleotides is comprosed of three amino acidsarrow_forward29. Dr. Doom wants to prevent a cell from entering the lysogenic pathway, which gene controlled by PRM would Dr. Doom target for inactivation? Group of answer choices 1. cro 2. cI 3. cII 4. Qarrow_forward
- 3. How might the regulation of the lac operon change if a point mutation occurred that blocks the ability of the repressor protein (LacI) to bind lactose?arrow_forward14. DNA methyltransferase, an enzyme that methylates DNA, - ---- a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b.. is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. . is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because a. the cell has just emerged from the quiescent G0 phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the Gl phasearrow_forward2. What is the role of the Promotor Region and the highly characterized promoter sequence, the TATA Box, in the process of DNA transcription? What nucleotides does the TATA box mainly consist of? ✓✓arrow_forward
- 10. Which statement is true about gene transcription? A. Every gene that is present in the genome is converted into a protein B. Only one of the two DNA strands is transcribed C. Every gene is transcribed to the same degree (makes the same amount of gene product) D. Transcription is different on the leading and on the lagging strandarrow_forward1. (a) The initiation factors form a complex with RNA polymerase Gene is switched ON Gene is switched OFF Does NOT affect the gene expression (b) RNA polymerase binds at the upstream region. Gene is switched ON Gene is switched OFF Does NOT affect the gene expressionarrow_forward2. Draw the chemical mechanism (with electron-pushing arrows) for the addition of an RNA nucleotide triphosphate to a growing mRNA transcript. Be sure to explicitly show the attacking nucleophile and the leaving group.arrow_forward
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