6. Retroviruses have an RNA genome instead of a DNA genome, and the RNA must becopied into the host's DNA. How does this process differ from other reactions inbiochemistry? What additional steps must happen for the virus to infect a cell?

Retroviruses are a type of virus that has a unique way of replicating their genetic material. Unlike…

Answered: 6. Retroviruses have an RNA genome…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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2. Bacteriophage are very specific in the types of cells they can infect. Some see this as a possible therapy to help treat against bacterial infections. Please discuss pros and cons of this type of therapy with proper support.
1. Name the molecule that contributes to the shape of a capsid around a virus?
83. Number the following stages in viral replication from 1 to 5 to show the correct order: replication attachment lysis and release entry assembly
2. If you were tasked to design compounds which will prevent viral attachment and entry into a host cell, which two viral-structural features would you target and why? Capside Ene ∙es attar
1. Predict the replication step (after it has entered the host cell) for the newly discovered Opiovirus. It has a dsDNA genome. • Draw out your prediction. Include any proteins/enzymes the virus will need to use, bring, or express to carry out the replication. Indicate where it is likely for replication to occur in the host cell.
8. Why are viruses considered non-living? a. Viruses cannot replicate on their own. b. Viruses do not carry out any metabolic processes. c. Viruses are not composed of cells. d. Viruses cannot detect and respond to environmental stimuli. e. All of the above.
2. Predict the replication step for the novel Miovirus. This virus was determined to have a dsRNA genome Draw out your prediction. Include any proteins/enzymes the virus will need to use, bring or express to carry out the replication. Indicate where it is likely for replication to occur in the host cell.
3. Name and describe the five steps of viral replication. Which step or steps differ the most between bacteriophage replication and animal virus replication? Why?
4. Describe the structure of the influenza virion. Explain how the form of the influenza genome enables the rapid evolution of novel strains that cause pandemics. Describe the replication cycle of the influenza virus. Differentiate between antigenic drift and antigenic shift.
1. If you knew the amino acid sequence of a peptide could you use that information to find the gene in a pool of genomic DNA. If so, how might you do this. 2. What is the difference between lytic and lysogenic viral replication?
3. Why is it more difficult to develop an antiviral drug than an antibiotic? Think selectively toxic targets. What is a virus made of? Why can’t we target DNA/RNA/Protein?

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6. Retroviruses have an RNA genome instead of a DNA genome, and the RNA must be copied into the host's DNA. How does this process differ from other reactions in biochemistry? What additional steps must happen for the virus to infect a cell?