How do sialic acid conformations explain the difference between influenza strains that infect humans and those that infect chickens?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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4. How do sialic acid conformations explain the difference between influenza strains that infect humans and those that infect chickens?
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An influenza pandemic is a worldwide outbreak produced by a novel influenza virus against which humans have little or no immunity. Influenza pandemics are unpredictable and can be mild or severe, resulting in disease or death.
Severe diseases that are comparable to those at risk of serious illness due to seasonal influenza may occur in certain risk categories. Because the pandemic in 2009 was caused by the influenza A virus, healthy persons can develop more severe infections than those caused by seasonal flu (H1N1).

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