24. Type 2 interferon is Interferon alpha Interferon beta Interferon gamma Only interferon alpha and beta

Paroxysmal nocturnal hemoglobinuria is a disease characterized by lysis of red blood cells, which results from the loss of____  on the cell surface, making them susceptible to the____ complement pathway.

_____antibodies are predominant in primary immune response,while _____________ antibodies are predominant in secondary immuneresponse

3. Complete the chart below by filling in the broad characteristics of each family of cytokines and which type of cell that secretes each one. Family name Interleukin-1 Class 2 (interferon) Class 1 (hematopoietin) IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-12, IL-13, IL-15, IL-21, IL-23, Representative members Characteristics Cell type that releases Interleukin-17 IL-1a, IL-1B, IL-Ra, IL- 18, IL-33 Chemokines GM-CSF, G-CSF, growth hormone, prolactin, erythropoietin, hematopoietin Tumor necrosis factor TNF-a, TNF-B, CD40L, Fas (CD95), BAFF, APRIL, LT-B IL-17 (IL-17A), IL-17B, IL-17C, IL-17D, IL-17F IL-8, CCL 19, CCL21, RANTES, CCL2 (MCP- 1), CCL3 (MIP-1a) IFN-α, IFN-ß, IFN-y, IL- 10, IL-19, IL-20, IL-22, IL-24