1. Which of these activities occur in ER? You can select more than one.TranscriptionTranslationrotein foldingA protein glycosylationanulphide bond formationO Addition of mannose6 phosphate5. ER experiences stress when ER protein-folding capacity is overwhelmed.leading to accumulation of misfolded proteins. Which of these factors cancause ER stress?Z Nutrient deprivationHypoxiaPoint mutation in secreted proteinsO loss of calcium homeostasis in ER lumenO smal sized ER7. What are the responses to ER stress?ncrease in the production of chaperonsIncrease in the production of degrading enzymesIncrease in the size of ER7ooptosisO O

Endoplasmic Reticulum- It is the largest single membrane- bound intracellular compartment or…

Answered: 1. Which of these activities occur in…

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter37: The Endocrine System

Section: Chapter Questions

Problem 1VCQ: Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In...

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In the normal cycle of Ras activity, when Ras is bound to y activity that removes a phosphate to convert GTP back to GDP and this it is inactive. Activation of Ras involves exchanging GDP for The Ras protein has intrinsic Ras. inactivates activates ATP GTP «< Questic A Moving to another question will save this response. ADP GDP GTPase Clo nuclease
E VG ✓H NA MATEN Match each letter (A through G) to its description. B A ya pada saat ada para a H F காலிமாம்ம் P S —— 1. Receptor 2. RNA 3. Lysosome 4. DNA 5. Ribosome 6. Ligand 7. Kinase domain 8. Nucleus 9. Mitochondria 10. Phosphorylated transcription factor 11. Dephosphorylated transcription factor 12. Plasma membrane
ras GDP ras ras P.P P.P GTP raf Inactive Active raf Inside of cell Refer to the figure above. A portion of a signal transduction pathway is shown in the figure. The molecule raf is a protein kinase. This molecule becomes activated when a GTP-ras complex binds to it. Which equation describes how activated raf transmits the signal in this pathway? O ATP. --> CAMP +PPi O CAMP --> AMP Inactive enzyme + ATP --> active phosphorylated enzyme + ADP O Inactive phosphorylated enzyme + ADP --> inactive enzyme + ATP Inactive enzyme + ADP --> active phosphorylated enzyme + ATP Assessment Navigator Submit Questionmark Ondemand licensed to University of Dundee PPIP
Which of the following is NOT regulated by glucagon? Glut-4 transporters protein kinase A Phosphorylase Hormone sensitive lipase O Gluconeogenesis The site of post-translational cleavage of biologically active proteins is often marked by: O methylated tyrosines. O pairs of basic amino acids. O disulfide bridges. O iodinated methionines. O heme-iron complexes. The selection of a specific promoter to activate during mRNA synthesis is determined by: O RNA polymerase I. O RNA primase. O a specific transcription factor. O cell cycle kinases. O RNA polymerase II.
The oscillatory clock that drives somite forma-tion in vertebrates involves three essential componentsHer7 (an unstable repressor of its own synthesis), Delta (atransmembrane signaling molecule), and Notch (a trans-membrane receptor for Delta). Notch is bound by Delta onneighboring cells, activating the Notch signaling pathway,which then activates Her7 transcription. Normally, thissystem works flawlessly to create sharply defined somites(Figure Q21–2A). In the absence of Delta, however, onlythe first five somites form normally, and the rest are poorlydefined (Figure Q21–2B). If a pulse of Delta is suppliedlater, somite formation returns to normal in the regionswhere Delta was present (Figure Q21–2C). A diagram ofthe connections between the components of the clockand how they interact in adjacent cells is shown in FigureQ21–2D. In the absence of Delta, why do the cells becomeunsynchronized? What is it about the presence of Deltathat keeps adjacent cells oscillating in synchrony?
1. EGF interacts with blank to activate the MAP kinase cascade? G protein coupled receptor; receptor Tyrosine kinase; serine/threonine kinase; cdk 2. When a trimetric G protein is activated by gpcf? The three subuni8of the G protein remain tightly associated with each other; the GDP bound to the a subunit is phosphorylated to form bound GTP; it dissociates into a free b subunit as an ay subunit; none
Phorbol esters have been observed to induce the transcription of AP-1–influenced genes. Explain how this processcould occur. What are the consequences of AP-1 transcription? What role does intermittent exposure to phorbol estershave on an individual’s health?
explain Mechanism of Myostatin Function & The PI3-K–Akt1 pathway
The amount of this in the cell rises as DNA synthesis begins. Cis-acting element that can increase transcription at a distant promoter. Encoded by, and required to propagate, Long INterspersed Element transposons. 1. steroid hormone The amount of this in the cell falls rapidly as DNA 2. steroid hormone receptor synthesis begins. Upon binding its ligand, it 3. DNA methyltransferase dimerizes and binds to a specific DNA sequence. 4. Adenosine deaminase Covalently modifies other proteins during a specific 5. Peptide hormone phase of the cell cycle. Regulatory signal that 6. Histone acetyltransferase binds to the extracellular domain of a receptor 7. Enhancer protein. 8. Recognizes and cuts a pair Reverse transcriptase of short inverted repeats in DNA. 9. Transposase Passes unassisted through membranes to bind to its target protein, which then activates gene expression. Base-modifying enzyme that changes the pairing properties of its substrate. Decondenses chromatin by neutralizing the…
Figure 16.13 An increase in phosphorylation levels of elF-2 has been observed in patients with neurodegenerative diseases such as Alzheimer’s, Parkinson's, and Huntington's. What impact do you think this might have on protein synthesis?
# 3 You've engineered a mutant cell where the FADD adapter was truncated. The mutant FADD only contains the Death Domain, and lacks the Death Effector Domain. What is the most likely phenotypic outcome for this mutant cell when presented with the Fas ligand? 20 E O The Fas/FasL oligomer is formed, but apoptosis is blocked O The Fas/FasL oligomer is formed, and apoptosis is hyperactivated O The Fas/FasL oligomer is not formed, and apoptosis is blocked O The Fas/FasL oligomer is not formed, but apoptosis is hyperactivated F3 $ 4 DOD 000 R F4 % 5 F5 T BARAT 6 tv @ MacBook Air F6 Y & 7 F7 U * ➤11 8 F8 · 9 F9
GTP binding proteins, which act as molecular switches inside cells activate by the GTPase action on the GTP are active only in their trimeric forms turn themselves on by phosphorylating GDP to form GTP activate immediately when GDP is released O are active when GTP is bound

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