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Explain the following:
1. What is immunologic agent drugs?
2. What is the importance of immunologic agent drugs to immunocompromised patients?
Step by step
Solved in 3 steps
- Can S-layer proteins be detected by immunolabelling when a capsule is present? How do you know? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/2. https://doi.org/10.1186/s12868-022-00692-1 (link to research) a) In the immunohistochemistry section of the materials and methods section the authors wrote “The number of positive cells in hotspot areas in ten high power fields (HPFs) in areas of demyelination and plaques in the brain stem were counted using the image analysis software (Lecia Application Suite Version 4.12.0, Welzlar, Germany).” Why were they looking at demyelination areas for this study? b) In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “Active plaques revealed inflammatory cellular infiltrates with abundant macrophages stuffed with myelin debris, an evidence of ongoing myelin breakdown.” What does macrophages stuffed with myelin debris have to do with the study?Shortly discuss the different immunodeficiency and immunoproliferative disorders and include the following: a. General Characteristic b. Cause c. Signs and Symptoms d. Clinical Diagnosis and Clinical Picture e. Immunologic Manifestations f. Treatment.
- What is severe combined immunodeficiency (SCID) ? Explain the symptoms & causes of severe combined immunodeficiency (SCID) ?5) In the event of an inflammation in the body, discuss the vaccine concept after stating what the proteins that cause this formation in the cell where the inflammation takes place and consequently cause the initiation of the fight against this foreign substance.With the aid of diagrams, discuss the role of autoantibodies in three named autoimmune diseases, then discuss how four named monoclonal antibody therapies (biologics) have been used to treat patients with autoimmunity in 2000 words.
- In relation to immunotechnology, answer the following: explain the reason behind developing different forms of Monoclonal antibodies (chimeric MABs, humanized MABs, and fully human MABs)What are the types of Immunomodulator agents? Please explain each of them? Please answer at your own words.A 41-year-old man has a penetrating injury to his right eye. A month later he has worsening vision in his left eye. Through which of the following immunoogic mechanisms has his vision in the left eye been reduced? a.Release of sequestered antigens b.Hypogammaglobulinemia c.Molecular mimicry d.T lymphocyte anergy
- explain these as an Immunotherapeutic approach for cancer therapy, 1. MONOLOCAL ANTIBODIES, 2. CHECKPOINT INHIBITORS, 3. CYTOKINES 4. CANCER VACCINES, 5. ADOPTIVE CELL THERAPY ( CAR T- CELL THERAPY) EXPLAIN EACH WITH ALL DETAILS ALL DETAILS NEEDED. I WILL DISLIKE IF IT’s SHORT ANSWER. OTHERWISE I WILL RATE :)What are the negative side effects of taking immunosuppressive drugs?Which of the followings is molecular pathology associated with ADA mutations that cause immunodeficiency? a) accumulation of deoxyadenosine and its precursors S-adenosylhomocysteine and deoxyadenosine triphosphate (dATP) with toxic effects on immature lymphocytes, b)accumulation of deoxyguanosine and deoxyguanosine triphosphate, with toxic effects on immature lymphocytes