1. Describe the morphological phenotypes you see in the experimental conditions, in comparison to the control condition. 2. Speculate what mutation or treatment could have caused the observed phenotype, and explain why. 3. Predict the functional consequence such morphological phenotype could have on mitochondrial functions, as well as its effect on cellular health and function. Case 3:  Two cells of two genotypes are being fused together.  Wild Type (WT) cell carries mitochondria whose matrix is tagged with GFP (green) while the other cell of unknown genotype carries mitochondria whose matrix is tagged with DsRed (red). The result of this fusion when the red cells is also WT is shown in the top row. Percentage of mitochondria appear to be fused is shown in the bar-graph to the right of the respective images. Please answer the 3 questions regarding the genotypes of the red cells in the middle and bottom row separately

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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1. Describe the morphological phenotypes you see in the experimental conditions, in comparison to the control condition.

2. Speculate what mutation or treatment could have caused the observed phenotype, and explain why.

3. Predict the functional consequence such morphological phenotype could have on mitochondrial functions, as well as its effect on cellular health and function.

Case 3:  Two cells of two genotypes are being fused together.  Wild Type (WT) cell carries mitochondria whose matrix is tagged with GFP (green) while the other cell of unknown genotype carries mitochondria whose matrix is tagged with DsRed (red). The result of this fusion when the red cells is also WT is shown in the top row. Percentage of mitochondria appear to be fused is shown in the bar-graph to the right of the respective images. Please answer the 3 questions regarding the genotypes of the red cells in the middle and bottom row separately

Case #3
Full Fusion
Partial Fusion
No Fusion
A
mito-EGFP
mito-DsRed
Merged
100
80
WT
Control
X
20
WT
Experimental 1
20
100
Experimental 2
20
Percent of cells
Percent of cells
Percent of cells
Transcribed Image Text:Case #3 Full Fusion Partial Fusion No Fusion A mito-EGFP mito-DsRed Merged 100 80 WT Control X 20 WT Experimental 1 20 100 Experimental 2 20 Percent of cells Percent of cells Percent of cells
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