Q8. (1) Complete the following genetic diagram to show how parents who did not suffer from haemophilia, could have a son wit h haemophilia but also other children who did not suffer from haemophilia. Phenotype of parents Genotype of parents Genotype of gametes Normal male Normal female Genotype of offspring Phenotype of offspring (1) What is the probability of the couple having a daughter with haemophilia? What is the probability of the couple having another son with haemophilia? (ii)

6. If individual IV-9 is a female, what is the probability that she would be affected with dark blue skin color?

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Type out the gametes that the mother and potential fathers can create  select all daddy's that can potentially be the father of baby Y explin why some fathers are being considered and why other potential fathers have been eliminatedwhich of the potential fathers is the actual dad of baby Y

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F. 9. If a man who is heterozygous marries a woman who is homozygous recessive, what would you predict for the genotypes and phenotypes of their children? Can a man and a woman who both suffer from hypercholesterolemia have children who do not have the disease? Explain your answer. Can a man and a woman have children with hypercholesterolemia if neither of them has the disease. Explain your answer. Hr homorgo

Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)] I. II. E III. IV. 1 1 2 2 3 1 3 1 4 2 4 5

8.     Huntington’s disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. A.     What is the genotype of a man who is normal but whose father had Huntington’s disease?   B.     What is the genotype of a woman who has Huntington’s disease if both of her parents had Huntington’s disease?   C.     If a man who is heterozygous for Huntington’s disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? D.     If a normal man marries a woman who is homozygous for Huntington’s disease, what do you expect for the genotypes and phenotypes of their children?

问题13 Achondroplasia (dwarfism) is an example of a dominantly inherited disease. Individuals who have the dominant gene (A) have the dwarfism phenotype, while normal height is recessive (a). What is the probability of having children with achondroplasia between a normal height female and a heterozygote achondroplasia male? 100% 75% 25% 50%

1. Is there a possibility that Joe's father has a genotype HH ? 2. The question does not mention that Joe's mother is hh.