1- Name of the disease/metabolic disorder due to deficiency of propionyl CoA carboxylase enzyme 2-Population affected; gender, age, race ... etc affected by previous disease or disorder 3- Symptoms of the disease/metabolic disorder (maximum 3 - 5 main common symptoms)
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- Maps EDD Debit Card H... Anthem Blue Cross:... JL Free 3rd Grade Mat... Question 5 of 16 Acetyl-CoA carboxylase is an important enzyme in fatty acid synthesis. It attaches carbon dioxide to acetyl-CoA to form malonyl-CoA. What coenzyme is covalently attached to acetyl-CoA carboxylase? A) thiamine pyrophosphate B) lipoic acid C) pyridoxal phosphate D) biotin E) tetrahydrofolateFor the mutation of the enzyme, describe the effect it will have on carbohydrate metabolism. Also, make sure to think about the effect it has on muscles versus the liver: Mutation that converted the active site cysteine in glyceraldehyde 3-phosphate dehydrogenase to a serineA carnitine deficiency might manifest itself as... accumulation of long chain fatty acids in the mitochondrial matrix. an inability to run ß-oxidation on 16-carbon fatty acids. excess medium chain fatty acyl-CoA molecules in the mitochondrial matrix. O ketoacidosis. the inability to synthesize long chain fatty acids.
- Trace the mechanism of Fatty acid oxidation using Palmitoleic acid - a 16-C containing fatty acid. Topic: Biochemistry (Lipid Metabolism)Give the process/pathway where each of the following enzymes is involved. _______________________ a. HMG CoA lyase _______________________ b. HMG CoA reductase _______________________ c. Acetyl CoA carboxylase _______________________ d. Acyl CoA dehydrogenaseDescribe the role of ethanol in cellular energy supply, the metabolism of ethanol (alcohol), the regulation of its metabolism and the disease conditions associated with its metabolism especially - hypoglycemia, ketoacidosis, hepatic steatosis, Vitamin deficiency, and acetaldehyde toxicity (you should feel free to discuss other diseases that are directly related to ethanol metabolism).
- -CHOOSE THE CORRECT LETTER- 1.Which of the following molecules were derived from acetyl CoA?A. amino acids, cholesterol, beta-hydroxybutyrateB.fatty acids, cholesterol, beta-hydroxybutyrateC. fatty acids, alpha-ketoglutarate, acetoacetateD. fatty acids, cholesterol, pyruvate 2.All the following statements about the free energy of glycolysis and gluconeogenesis are true, EXCEPTA. The conversion of glucose to 2 lactate yields a net of 2 ATPB. The conversion of glucose to 2 pyruvate yields 2 NADH and a net of 2 ATPC. The conversion of 2 pyruvates to glucose requires 4ATP, 2 GTP and 2 NADHD. Gluconeogenesis requires 6 more ATP per glucose that what were derive from glucose to glycolysisIndicate what will happen (increase, decrease or no effect) to the activity of enzyme or rate of the metabolic pathway given the following conditions: 1. release of glucagon in the blood to the activity of carnitine acyl transferase 1 2. phosphorylation of acetyl CoA carboxylase 3. low [carbon dioxide]/[oxygen gas] ratio to the oxygenase activity of RuBisCOA. What would happen in the Krebs cycle with the loss of activity of phosphoglycerate kinase? What would happen in glycolysis? 10. What happens to glycolysis with the addition of high amounts of citrate? What happens to ETS? 11. What happens in the Krebs cycle with a block in fumerase? 12.If an amino acid enters the Krebs cycle at the acetyl CoA entry point, how much more ATP is being made than if it enters at a keto-glutarate?
- For the mutation of the enzyme, describe the effect it will have on carbohydrate metabolism. Also, make sure to think about the effect it has on muscles versus the liver: Mutation that converted the active site glutamate in phosphohexose isomerase to an glutamine.Match the appropriate terms to their definitions TCA cycle or tricarboxylic acid Choose.. cycle Choose. aerobic the pathway in which glucose is metabolized to lactate in the muscle, lactate is converted back to glucose in the liver, and then glucose is returned to the muscle the making of glucose from a noncarbohydrate source such as amino acids or glycerol requiring oxygen anaerobic the metabolic breakdown of glucose to pyruvate not requiring oxygen. a series of metabolic reactions that break down molecules of acetyl CoA to carbon dioxide and hydrogen atoms Cori cycle Choose.. glycolysis Choose... gluconeogenesis Choose...Define a ketogenic diet and give an example of a ketogenic meal. Explain why ketone supplements would not be a useful alternative to the ketogenic diet as a cancer therapy. Why might dietary treatments be preferred over conventional treatment options?
