Phlebotomy Essentials
6th Edition
ISBN: 9781451194524
Author: Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher: JONES+BARTLETT PUBLISHERS, INC.
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- How are antibodies unique? Please discuss the structure of an antibody. What are the V and C regions? Discuss how the few hundred genes involved are capable of making endless amounts of antibodies. Besides medical treatment what is another way antibodies can be used?arrow_forwardA 10 year old girl is sent to the school nurse one hour after getting a splinter on her right index finger.. Examination of the finger shows the splinter end, extending from the fingertip; the surrounding area is erythematous, Edematous,and tender. Which off the following molecules, has a primary role in mobilizing neutrophils from the vasculature into the area of the splinter? A) complement component 3B B) C-reactive protein C) factor 12( hageman factor) D) fibrinopeptide E) intracellular adhesion molecule onearrow_forwarda) What is a secondary antibody and why is it used? b) What is the specific substrate for HRP? What color does it produce?arrow_forward
- What scenario best describes an autoimmune reaction? Group of answer choices The destruction of donated red blood cells by the recipient’s immune system The production of antibodies against Streptococcus pyogenes antigen resulting in cross-reaction against an antigen found on heart valves The activation of Mast cells by pollen The production of antibodies against Streptococcus pyogenes resulting in the deposit of antigen-antibodies in the kidney leading to glomerulonephritisarrow_forwardMatch the following term with its description or definition. Immunoglobulin domain Amino acids that are separated in the protein chain but come together in the folded protein Antigen that carries several epitopes of the same or different specificity Heavy chain classes Soluble proteins that carry only one copy of the epitope ✓ Choose... IgG, IgM, IgD, IgA, IgE Multivalent antigen Discontinuous epitope Monovalent antigen Repeated barrel-shaped structure Choose...arrow_forwardThe figure above depicts an antibody. For the labeled areas, which statement among A-D is not correct? A) O Mature, functional IgA antibodies possess a total of two sites labeled A B) O Your IgM antibodies are all similar in these areas: A C) O During opsonization, area B would bind to a bacterium D) O Your IgD antibodies are all different in this area: B 111 E) O None are matched correctly. B.arrow_forward
- Explain why IgM has a stronger power of agglutination than antibodies of any other class.arrow_forward1. The laboratory scientist who reviews the marrow reports that the bone marrow is overridden with plasma cells—so much so that clusters of plasma cells can be seen. What is the function of plasma cells? Explain with no more than 3-6 sentences. A). To present foreign antigens to immune cells B). To directly attack foreign cells when foreign antigens are recognized. C). To phagocytize cells with foreign antigens. D). To produce immunoglobulins specific to foreign antigens presented by T helper cells. 2. Immunoglobulins are made mainly of what substance? Explain. A). Carbohydrate B). Lipid C). Proteinarrow_forwardMatch the types of immunity written on the table with the descriptions below. Write the number corresponding to the type. 1. Innate 3. Natural-active 5. Natural- passive 7. Antibody-mediated 2. Acquired Adaptive 4. Artificial-active 6. Artificial-passive 8. Cell-mediated 1. The body is producing antibodies as a result of bacterial infection. 2. An adaptive immune response involving T lymphocytes. 3. It occurs when we receive vaccines of attenuated antigens. 4. This immunity is highly specific to the pathogen; has a memory. 5. This involves the B lymphocytes that give rise to antibodies. 6. This is a generalized defense against all foreign invaders. 7. It happens when a person receives infusion of gamma globulins. 8. It is passed on from the mother onto a fetus through placenta.arrow_forward
- Match the antibody classes with their characteristics: IgM IgG IgA IgE IgD Most efficient for agglutination Most abundant in blood; easily penetrates tissue spaces Most abundant in mucus; traps pathogens in mucus Located on the surface of B cells; trace amounts can be found in serum Least abundant; helps stimulate inflammatory responsearrow_forwardWhich antibody type description among A- D is falsely characterized? A) O IgA: form dimers; prevent adherence of pathogens to mucosal surfaces 1f1 B) O IgG: circulating antibody with multiple functions; formed in high numbers in secondary antibody response C) O IgM: forms multimers whose function is agglutination of infectious microbes D) O IgE, IgD: carry out their function while bound to the surfaces of specific cell types E) O None are false, A-D are all correctarrow_forwardWhich of the following characteristics apply to this cell 1. affected cell in mononucleosis 2. # 1 in frequency 3. synthesizes and releases cytokines 4. phagocytic 5. synthesizes and releases antibodies Choose from the following: (A) 1 and 2 (B) 3 and 5 (C) 2 and 3 (D) 2, 3, and 4 (E) 4 and 5arrow_forward
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