Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
CATGATACAAGGCCCTTCCGGTACAACCACTTCGGTAGAAAGCCTTTCGGAGACCGTCCCTTOGGCAGACGCAACmI cear CA PESCA CROOngm O uaNOCIGa P L CEIC00PORMORlg mcaGccCTTCCGGT 916
10 5'UTR 20|JATG 3b
50 Leader 60
80
100
1
110
130
160 2
40
70
90
120
140
150
170
180
190
....I....I....I....I.. ..r....I........I....I....I....I....I....I........I....I....I....I....I....I....l....I....I........I....I....I.......I....I....I....I....I....I....I.........I
.1....I....
DQ183132
DQ183133
DQ183134
...2
-TCGGAGAGACTATTACTAACATG
TCGGAGAGACСТАТТАСТААФАТО
TCGGAGAGACCTATTACTAACATG
3
GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCCCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185
GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCGCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185
GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCCCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185
| 220
4 260
.--
200
210
230
240
250
270
280
290
300
310
320
5
330
340
350
360
370 6...
380
GTTCGATGGACCT 300
STTCGATGGACCT 300
STTCGATGGACCT 300
8...
570
1....I....
GGATTTGGTGCCCCCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGGGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGATGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTO 490
GGATTTGGTGCCCCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGAGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGTTGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTO 490
cCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGGGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGATGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTd 490
AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAAGAG
AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAGGAG
AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAGGAG
..6
7
510
390
.I....I.
400
410
420
430
440
450
460
470
480
490
500
520
530
540
550
560
1....
1..
.1....I....l..
1......
.1....I....I..
1....I.... !....I....I..
.I.....I.
1....I.... I....I.
..I.
...I.....
...I..
GGATTTGGTO
---
8
8 580
9590
600 10
66011а-b 670
710
12 720
740 13... 750
730
GTCACCGTCAAGGTCATCCTCAGGATCAAGC 566
GTCACCGTCAAGGTCATCCTCAGGACCAAGC 566
GTCACCGTCAAGGTCATCCTCAGGACCAAGC 566
610
620
630
640
650
680
690
700
760
TAGGAGGGCCCGGTCAGTTTGATGGTCCTGGACGTCGTCATCATG
TAGGAGGGCCCGGTCAGTTTGATGGTCCTGGACGTCGTCATCATG
FAGGAGGGCCCGTOAGTTTGATGGTCCTGGACGTCGTCATCATG
...13 770
850 15а-е g60
ACCATGGCCACCAC
14
16 900
910
920 17... 930
780
790
800
810
820
830
840
870
880
890
940
1....I.... I
950
..I....I....
AGAGGAACAACCGTTIGGICACCGCAACG
AGAGGAACAACCGTTTGGTCAGCGCAACGAAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCC
AGAGGAACAACCGTTTGGTCAeCGCAACGAAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCO-t
. 1
GAGACGGGAGATCAAGATCAGGACAAACTA 726
1..
...I.
1.
........I.
CACCGT
CATCATAACCACACAGAAGGTCACCAAGGTCATAAT
CATCATAACCACACAGAAGGTCACCAAGTTCATAAT-
CATCATAACCACACAGAAGGTCACCAAGGTCATAAT
...
....
AAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCC
ACCATGGCCACCAC
САСCGT
GAGACGGGAGATCAAGATCAGGACAAACTA 726
-ACCATGGCCACCAC
CACCGT
GAGACGGGAGATCAAGATCAGGACAAACTA 726
11bo 21... 1140
1330
....I....I....I....I....I....I.... ....I....I........I.... I....1....I....I....I....I....I....I....I....I....I....I.... ....I....I........I....I....I....I....I....I....I....I.... ....I....I
СATGATACAAGссссттссGGTACAAСCАСTTCоTAGAAAGCCTTTcGGAGACCGTCCсттфссAGACGСAАССАТАCAGAАGGTCACCGGGGTтсАТAАTGAGACGGGAGACCACCCсСАТCGTCATCACAACAAGACCAGAGATGGACATCAGGACAGACCAATGTTCGAGATGAGCессттссGGT 916
CATGATACAAGGCCCTTCCGGTACAACCACTTCcCGTAGAAAGCCTTTCGGAGACCGTCCCTTCGGCAGACGCAACCATACAGAAGTTCACCAGGGTCATAATGAGACGGGAGACCACCCCCATCGTCATCACAACAAGACCAGAGATGGAGATCAGGACAGACCAATGTTCGAGATGAGCcCCTTCCGGT 916
САTGATACAAGGCCCтTCCGGTАCAACCАСТТCсеTAGAAAGCCтттсGGAGACCGтCСсттоGCAGACGCAACCAТАCAGAAGGTCАСCAGGGTCATААTGAGACGGGАGACCACCCCCAТСGTCATCACAАCAAGACCAGAGATGGACTCAGGACAGACCAAТСттCGAGATGAGCCCСттссGGT 916
960 ...17 970
980
990
18 1000
1010
1020
1030
1040
1050
1060 19
1070
1080
1090
1100
1110 20 1120
...21
1150
1160
22 1170
1180
1190
1200
1210
1220
1230
1240
1250 23... 1260
1270
1280
1290
1300
1310
1320
TCAACCCCTTCGGTGGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC
TCAACCCCTTTGGTAGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC
TCAACCCCTTCGGTAGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC
969
969
969
1340
1350
1360
1370
1380
1390
1400
1410..23...1420
1430
1440
1450
1460
1470
1480
1490
1500
1510
1520
....I....I....
1.
1....I
1....
....
969
969
969
...23 1530
1570 24
1..
1540
1650 25a...1660
1910
. ..J.......]........|................|....|....|....|....J....|....|........|........|
GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCCTATGGTAACCGAGGACGATGGGGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068
GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCcCTATGGTAACCGAGGACGTTGGAGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068
GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCCTATGGTAACCGAGGACGATGGGGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068
1550
1560
1580
1590
1600
1620
1630
1640
1670
1680
1690
1700
1710
..L...
.|....|.….
Stop 1
Stop 2
18de
Stop 3
18UTR..pe90
1770 25b 1780
1830 25c 1840
....|....|....|...|.... |..].…..
1720...25a1730
1740
1760
1790
810
1820
1850
1870
-...]..
....|....|....|....|.... |..]. |....|........J....|....|....|....|....|....|.... |.
ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC------
ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC-
ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC
AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTTTTT-
AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTTTTT-
AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTT
-1.......|....|....|....|....|....|.
TARATATA
TAPATATA
TAATATA
AAAATATTGCTTGTG
TTGATAATAGT-CATCAATGTC 1207
TTGATAATAGT-CATCAATGTC 1207
TTGATAATAGT-CATCAATGTC 1207
-AAAATATTGCTTGTG
AAAATATTGCTTGTG
missing sequence?
in the indel for that element)
a. Which elements in the above alignment have missing sequence? (ONLY list those elements
а.
where there are NO nucleotides present
b. Using the reference image, what element pattern do these sequences display?
expand button
Transcribed Image Text:CATGATACAAGGCCCTTCCGGTACAACCACTTCGGTAGAAAGCCTTTCGGAGACCGTCCCTTOGGCAGACGCAACmI cear CA PESCA CROOngm O uaNOCIGa P L CEIC00PORMORlg mcaGccCTTCCGGT 916 10 5'UTR 20|JATG 3b 50 Leader 60 80 100 1 110 130 160 2 40 70 90 120 140 150 170 180 190 ....I....I....I....I.. ..r....I........I....I....I....I....I....I........I....I....I....I....I....I....l....I....I........I....I....I.......I....I....I....I....I....I....I.........I .1....I.... DQ183132 DQ183133 DQ183134 ...2 -TCGGAGAGACTATTACTAACATG TCGGAGAGACСТАТТАСТААФАТО TCGGAGAGACCTATTACTAACATG 3 GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCCCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185 GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCGCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185 GTGAAAGTGACACTGATCGTTGCCATTGTGGCTGCTCTTGCTATCTCAGCTCACGCACAAAGAGATTACAATGAACTACGAGGAAATAAGAATGGCAGAGAGAGAGGACAAGGTCCCTTTGGAGGAAGGCCGGGTGGAATGCAGATGGGTGGATCGAGGCA 185 | 220 4 260 .-- 200 210 230 240 250 270 280 290 300 310 320 5 330 340 350 360 370 6... 380 GTTCGATGGACCT 300 STTCGATGGACCT 300 STTCGATGGACCT 300 8... 570 1....I.... GGATTTGGTGCCCCCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGGGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGATGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTO 490 GGATTTGGTGCCCCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGAGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGTTGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTO 490 cCGGAGATGGATGGACGGAGACAAAATGGCGGTCCGATGGGTGGAAGGAGATTCGACGGACCTGGATTTGGTGGCTCCAGACCAGATGGTGCTGGAGGAAGACCTTTCTTCGGCCAAGGAGGCAGGCGTGGTGATGGAGAAGAAGAAACTGATGCTGCCCAACAAATTGGTGATGGTd 490 AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAAGAG AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAGGAG AGATGGTGGACCAATGGGTGGAAGAAGGTTCGATGGACCTGACTCTGGTGCCCCACAAATGGATGGACGGAGACAAGATGGTGGACCAATGGGTGGAAGGAG ..6 7 510 390 .I....I. 400 410 420 430 440 450 460 470 480 490 500 520 530 540 550 560 1.... 1.. .1....I....l.. 1...... .1....I....I.. 1....I.... !....I....I.. .I.....I. 1....I.... I....I. ..I. ...I..... ...I.. GGATTTGGTO --- 8 8 580 9590 600 10 66011а-b 670 710 12 720 740 13... 750 730 GTCACCGTCAAGGTCATCCTCAGGATCAAGC 566 GTCACCGTCAAGGTCATCCTCAGGACCAAGC 566 GTCACCGTCAAGGTCATCCTCAGGACCAAGC 566 610 620 630 640 650 680 690 700 760 TAGGAGGGCCCGGTCAGTTTGATGGTCCTGGACGTCGTCATCATG TAGGAGGGCCCGGTCAGTTTGATGGTCCTGGACGTCGTCATCATG FAGGAGGGCCCGTOAGTTTGATGGTCCTGGACGTCGTCATCATG ...13 770 850 15а-е g60 ACCATGGCCACCAC 14 16 900 910 920 17... 930 780 790 800 810 820 830 840 870 880 890 940 1....I.... I 950 ..I....I.... AGAGGAACAACCGTTIGGICACCGCAACG AGAGGAACAACCGTTTGGTCAGCGCAACGAAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCC AGAGGAACAACCGTTTGGTCAeCGCAACGAAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCO-t . 1 GAGACGGGAGATCAAGATCAGGACAAACTA 726 1.. ...I. 1. ........I. CACCGT CATCATAACCACACAGAAGGTCACCAAGGTCATAAT CATCATAACCACACAGAAGGTCACCAAGTTCATAAT- CATCATAACCACACAGAAGGTCACCAAGGTCATAAT ... .... AAAGCAGCGAGGAGGATGGCCGTCCTCACCCTCACCACCATCGCC ACCATGGCCACCAC САСCGT GAGACGGGAGATCAAGATCAGGACAAACTA 726 -ACCATGGCCACCAC CACCGT GAGACGGGAGATCAAGATCAGGACAAACTA 726 11bo 21... 1140 1330 ....I....I....I....I....I....I.... ....I....I........I.... I....1....I....I....I....I....I....I....I....I....I....I.... ....I....I........I....I....I....I....I....I....I....I.... ....I....I СATGATACAAGссссттссGGTACAAСCАСTTCоTAGAAAGCCTTTcGGAGACCGTCCсттфссAGACGСAАССАТАCAGAАGGTCACCGGGGTтсАТAАTGAGACGGGAGACCACCCсСАТCGTCATCACAACAAGACCAGAGATGGACATCAGGACAGACCAATGTTCGAGATGAGCессттссGGT 916 CATGATACAAGGCCCTTCCGGTACAACCACTTCcCGTAGAAAGCCTTTCGGAGACCGTCCCTTCGGCAGACGCAACCATACAGAAGTTCACCAGGGTCATAATGAGACGGGAGACCACCCCCATCGTCATCACAACAAGACCAGAGATGGAGATCAGGACAGACCAATGTTCGAGATGAGCcCCTTCCGGT 916 САTGATACAAGGCCCтTCCGGTАCAACCАСТТCсеTAGAAAGCCтттсGGAGACCGтCСсттоGCAGACGCAACCAТАCAGAAGGTCАСCAGGGTCATААTGAGACGGGАGACCACCCCCAТСGTCATCACAАCAAGACCAGAGATGGACTCAGGACAGACCAAТСттCGAGATGAGCCCСттссGGT 916 960 ...17 970 980 990 18 1000 1010 1020 1030 1040 1050 1060 19 1070 1080 1090 1100 1110 20 1120 ...21 1150 1160 22 1170 1180 1190 1200 1210 1220 1230 1240 1250 23... 1260 1270 1280 1290 1300 1310 1320 TCAACCCCTTCGGTGGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC TCAACCCCTTTGGTAGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC TCAACCCCTTCGGTAGAAAGCCTTTCGGAGGCCGTCCCTTCGACAGACGCAAC 969 969 969 1340 1350 1360 1370 1380 1390 1400 1410..23...1420 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 ....I....I.... 1. 1....I 1.... .... 969 969 969 ...23 1530 1570 24 1.. 1540 1650 25a...1660 1910 . ..J.......]........|................|....|....|....|....J....|....|........|........| GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCCTATGGTAACCGAGGACGATGGGGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068 GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCcCTATGGTAACCGAGGACGTTGGAGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068 GGAACCGAAGAAGGATCTCCCAGGCGTGATGGCCATCGTCGGCCCTATGGTAACCGAGGACGATGGGGTGAGAATGAAAGTGAGGAGAAGGAGCATCCA- 1068 1550 1560 1580 1590 1600 1620 1630 1640 1670 1680 1690 1700 1710 ..L... .|....|.…. Stop 1 Stop 2 18de Stop 3 18UTR..pe90 1770 25b 1780 1830 25c 1840 ....|....|....|...|.... |..].….. 1720...25a1730 1740 1760 1790 810 1820 1850 1870 -...].. ....|....|....|....|.... |..]. |....|........J....|....|....|....|....|....|.... |. ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC------ ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC- ACGACGGAAAGCGTAACGACATCTTCACCACCTGAAGTGGTCGCAATC AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTTTTT- AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTTTTT- AATGAAGAAGACATCAATGTGGTCGCCGAGGTGTAGAATTTGTT -1.......|....|....|....|....|....|. TARATATA TAPATATA TAATATA AAAATATTGCTTGTG TTGATAATAGT-CATCAATGTC 1207 TTGATAATAGT-CATCAATGTC 1207 TTGATAATAGT-CATCAATGTC 1207 -AAAATATTGCTTGTG AAAATATTGCTTGTG missing sequence? in the indel for that element) a. Which elements in the above alignment have missing sequence? (ONLY list those elements а. where there are NO nucleotides present b. Using the reference image, what element pattern do these sequences display?
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