. Of the two unimolecular reactions shown, decide which you think would be faster, i.e., which would have a higher relative rate constant (krel)? 2. Based on your answer, draw two lines on one reaction coordinate diagram that show the relative progress of each reaction along its path to product indicated? 3. what is Bond dissociation energy of the C-LG bond? 4. what is the Nature of the leaving group (LG)? 5. what is the relative size of activation energy (Ea) for each reaction? 6. what is the Hammond's postulate? 7. what are the Relative thermodynamic stability of the reactive intermediates? 8. what is Influence of the solvent (if given) on the reactions and intermediates?

6. Consider the following reaction: CH3 HBr. ? ČH3 a) Draw the two possible allylic cations that could be produced as an intermediate in this addition reaction; include resonance structures. b) Which of these allylic cations is more stable, explain briefly how you arrived at that conclusion? c) Draw the complete mechanism for the addition reaction involving the more stable allylic cation intermediate showing the formation of both the 1,2 and 1,4 addition products, include arrows, formal charges and electron pairs. d) If the reaction is carried out at 0°C, what would be the major product? e) The reaction is then carried out at 80°C, and the major product was found to be the same as when the reaction was carried out at 0°C. What is the kinetic product and what is the thermodynamic product? f) Assuming the first step is rate determining, and the reaction is spontaneous, sketch a reaction coordinate (energy diagram) for the mechanism drawn in part c). Label the reactants, products (kinetic…

Draw the major organic product(s) of the following reaction. Br + NaSCH3 acetonitrile • You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. • When SN1 & E1 pathways compete, show both the substitution and the elimination products. Separate multiple products using the + sign from the drop-down menu. • Do not include counter-ions, e.g., Na*, I', in your answer. [ ] در

Draw the major organic product from the reaction sequence. Select Draw Rings More Erase H. 1. Excess CH3MGBR 2. H3O* 3. NaH, THF 4. CH;CH2CH,Br