Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
Consider the Friedel-Crafts (FC) alkylation of N-phenylacetamide (shown below) in which a reaction with 1-chloropropane and AlCl3 produces two isomers of isopropyl N-phenylacetamide.
1. Draw the complete reaction mechanism for the formation of the ortho product (para is also formed).
2. Is this reaction faster or slower than the similar FC reaction starting with benzene (C6H6)? Explain why.
3. Explain why this reaction produces the ortho and para products (but not meta).
Use your mechanism to help explain parts #2 and #3. Use additional drawings and words as needed.
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