Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- Which of the following is incorrect about the conversion of acetyl-CoA (2 C) to malonyl- COA (3 C)? O a. It is irreversible O b. O c. It is a decarboxylation It is regulated Od. It is the first step of fatty acid synthesis +arrow_forwardWhich enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferasearrow_forwardHow many NADH, FADH2, NADPH and ATP will be generated when breaking this fatty acid down into molecules of Acetyl-CoA (16:1Δ9)?arrow_forward
- Answer all the following questionsarrow_forwardWhat are the direct products of b oxidation of a fully saturated, straight-chain acyl-CoA of 13 carbons? How many ATP molecules can be obtained from complete oxidation of this compound?arrow_forwardif each NADH generates 3 ATP molecules and each FADH2 generates 2 ATP molecules, calculate the number of ATP molecules generated from one saturated 10-carbon fatty acid Determine the number of repetitions of the β‑oxidation spiral needed to completely degrade the fatty acid to acetyl-SCoAacetyl-SCoA (acetyl-CoA)(acetyl-CoA) . Calculate the ATPATP produced by the acetyl-SCoAacetyl-SCoA molecules in the citric acid cycle. Calculate the ATPATP produced from the FADH2FADH2 and NADHNADH produced from β‑oxidation. Add the ATPATP generated (from step 2 and 3), and subtract the ATPATP needed to activate the fatty acid.arrow_forward
- Fill in the blanks with the numerical answer only: Number of electrons generated in oxidation of 1 glucose to 2 pyrvuate in glycolysis. Number of electrons generated in the oxidation of 2 pyruvate by pyruvate dehydrogenase complex. Number of electrons generated for complex II in oxidation of 2 acetyl CoA via the TCA Cycle.arrow_forwardBefore a fatty acid can undergo B-oxidation it must be: O Transport of the FA into the mito. matrix O Hydrolysis of the carboxyl group from the FA O Carboxylation of Acetyl-CoA to form malonyl-CoA Activation of the FA with Coenzyme A O Oxidation of the FA yielding a A2-enoyl intermediatearrow_forwardWhich of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.arrow_forward
- I don't understand it. Can you help me? Can u help me to explain this to me, please?arrow_forwardOH The usage of acetyl-CoA in the cell depends on the metabolic / physiological state of the body. The table below shows the possible uses of acetyl-CoA, the corresponding physiological states of the body and the organ/cellular location where these processes occur. Identify which option is correct. Option Use of acetyl-CoA 1 2 3 4 Ketogenesis Cholesterol synthesis OOOO Fatty acid synthesis Oxidation via the citric acid cycle Select one: a. Option 1 b. Option 2 c. Option 3 O d. Option 4 Metabolic / Physiological state of the body Fasting state Fasting state Well fed Well fed Organ and cellular site Most cells / mitochondria Liver / cytoplasm Adipocyte / mitochondria Red blood cell / mitochondria Report question issue Noarrow_forwardSelect the BEST answer. Increasing the concentration of Fructose-2,6 bisphosphate would Inhibit Phosphofructokinase 2 Increase the concentration of Fructose-1,6 bisphosphate (phosphofructose isomerase) O increase the synthesis of glycogen Increase the carboxylation of Ac-CoA to make more malonyl-CoA increase the concentration of Pyruvatearrow_forward
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