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Medullary Reticular Formation Essay

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During REM sleep there are numerous output fibers from REM sleep triggering regions that go towards the medial medullary reticular formation, some of which have synaptic contacts with the neurotransmitter serotonin, that contain medullary neurons. The efferent pathway that connects to the pontine REM regions, which have cells of the medial medullary reticular formation, may be important for moderating sleep-specific inhibitory or excitatory postsynaptic effects in motor neurons, and silencing medullary serotonin containing cells. In the dorsomedial pontine, some axon terminals emanate from there that make synaptic contacts with medullary reticular formation cells that dispatch axons to the hypoglossal motor nucleus. These cells mediate REM sleep-related inhibitory or excitatory synaptic potentials that occur in motor neurons associated with REM. …show more content…

The VLPO , also known as the “sleep switch” , as well as the anterior thalamus and basal forebrain are activated, which inhibits the arousal system. Particularly, the VLPO, GABA and galanin containing neurons, inhibit and project wake-promoting regions of the ascending reticular system and descending brainstem arousal neurons. During the activation of cholinergic neurons in the pedunculopontine and laterodorsal tegmental nuclei, REM occurs. The withdrawal of the aminergic arousal system produces inhibition during cholinergic activation. As a result, this causes AcH release, that triggers neural activity increase that features in

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