Acute Promyelocytic Leukemia Research Paper

This movie called My Sister’s keeper is a film that is all about a couple’s life that has a daughter named Kate. Kate was diagnosed with promyelocytic leukemia. Promyelocytic leukemia (PL) is a malignancy of the bone marrow in which there is a lack or insufficiency of mature blood cells in the myeloid line of cells and an excess of immature cells called promyelocytes. PL is due to a translocation (an exchange of chromosome material) between chromosomes 15 and 17 which is symbolized t(15; 17). This translocation is not a mere marker of PL. It is the cause of PL (MedicineNet, n.d.). Gordon’s functional health assessment pattern was use in this presentation. The patient’s culture, geographic, religious, ethnic or spiritual and sexual concerns

In Boston, Massachusetts, small groups of families sued US companies due to the constant leukemia and health deaths, caused by the poisonous chemicals dumped in the water, which got flowed into the communities water supply. Anne Anderson discovered that her child had leukemia. Searching for the cause, its discovered that there's a cluster of children with leukemia. Anderson, as well as the other families affected by the water, evolve into a law suit against two large companies.

Low blood counts are a key feature of myelodysplastic syndrome which is the reason for the many symptoms these patients experience. The three types of cytopenia that people with Myelodysplastic Syndrome experience are anemia, neutropenia, and thrombocytopenia which are all low blood cell counts of the three blood cells. Cytopenias can cause anemia, the inability to fight off infections, easy bruising, and spontaneous bleeding. This can be due to the lack of blood cells in the blood stream, but also from dysplasia of the blood cells from the disease. If the cell is deformed, it may not be able to provide the same function as a healthy cell, resulting in the same effect as having cytopenia. Myelodysplastic syndrome is a gradual process and is

In the film My Sister's Keeper a very sick girl named Kate (Sofia Vassilieva) has Acute Promyelocytic Leukemia which is a cancer of the white blood cells so to get the treatments that Kate needs her parents Sara (Cameron Diaz) and Brian (Jason Patric) go to extreme measures and genetically engineering a new child by altering the genes of the egg and sperm to create an identical match to Kate so that this new child could be a donor for Kate's treatments. They show the social issue very well by having this new child Anna (Abigail Breslin) and using her body parts for treatments for Kate when she is a newborn. In the book when their mother Sara had Anna she didn't care about the newborn she was just worried about the umbilical cord which they

Acute Lymphoblastic Leukemia, is the disease that affects children the most and because of the abnormal cells that are immature white blood cells which cannot help the body fight infections cause children with the disease to often get infections and have fevers (National Cancer Institute, 2002, p. 1). The symptoms that the patient with ALL may have depend on the number of abnormal cells of the patient where exactly the cells collect. Children patients with ALL have low amounts of healthy red blood cells and platelets, which cause less oxygen to be carried through the body because of the lack of red blood cells. Patients at times may look pale, feel weak, and tired causing bleeding and bruising very easily because of their lack of enough platelets. This condition is called anemia. Anemia is very much common in patients with acute lymphoblastic leukemia. Fever, fatigue, bone or joint pain, tiny red spots under the skin called petechiae are a couple of symptoms that the disease ALL has. Headaches with, or without vomiting also may occur if patient happens to have abnormal cells collecting in the brain or spinal cord (National Cancer Institute, 2002 para. 2).

After their successful work with Acute Lymphoblastic Leukemia, St. Jude Children’s Hospital decided to expand their efforts outwards and focus on another type of leukemia that attacks the lives of children every year. Acute Myeloid Leukemia, a cancer that begins in bone marrow and quickly multiplies and spreads to white blood cells, makes up 20% of all childhood leukemia (Pui 51). The first AML study at St. Jude began in 1986. Before the start of this project, only one child out of every 58 children suffering from this illness survived for a time greater than five years; however, by the end of the first study completed in 1973, the rate of remission had increased to 66%. Although St. Jude was ecstatic that they had brought the rate of remission

Aplastic Anemia is a rare disease in which a person’s bone marrow fails to produce new blood cells. Bone marrow is the spongy tissue found in some of our bones and is responsible for blood cell formation, hematopoiesis. Our bone marrow is given the task to generate red blood cells, which carry oxygen, white blood cells, which fight foreign entities, and platelets, which are responsible for blood clotting. In children, bone marrow is found in the long bones such as the femur, and in adults it is mostly found in flat bones such as the sternum and pelvic girdle. Patients who are diagnosed with Aplastic Anemia are deficient in all three blood cells, due to damage to

S.L. is a 34-year-old male that arrived at his primary care provider’s office today for what he states is his fourth “cold” this year. He proclaims that he has been coughing non-stop and feels congested. He denies taking his temperature but has felt occasional sweats and chills. This being his fourth visit to his primary care provider for the same signs and symptoms. At the previous visits, he was diagnosed with upper respiratory infections that only antibiotics such as amxocillin seem to clear up. Other medical management he has tried has been acetaminophen for

The age-adjusted incidence of acute myeloid leukemia is 3.6 per 100000 persons per year, with a median age of 66 years at diagnosis. Whereas the outcome for patients with AML who are less than 60 years of age has improved over the past several decades, the major reasons for failure are primary refractoriness of the disease to initial chemotherapy or failure to maintain the complete state of remission.. Some patients have residual leukemic cells in their marrow even after intensive treatment. This is referred to as “refractory leukemia.” There are other patients who have a return of leukemia cells in the marrow and a decrease in normal blood cells after achieving a remission. This is referred to as “relapsed leukemia.” (Leukemia and Lymphoma Society 2011)

“All it takes is one small mistake anywhere in the division process for cell to start growing out of control (…) Just one enzyme misfiring, just one wrong protein activation, and you could have cancer.”

Acute Lymphocytic Leukemia is a scary disease. The term “acute” means the disease can quickly spread and progress quickly and can prove fatal in months if left untreated. “Lymphocytic” simply means that it develops from immature forms of lymphocytes. Also known as Acute Lymphoblastic Leukemia, or ALL for short, it is a type of cancer that starts from the early form of white blood cells called lymphocytes in the bone marrow. ALL is the most common form of cancer in children, though adults can get it as well. For children, treatment results in a good chance of a cure. Adults have a significantly smaller chance of a cure with ALL. ALL generally invades the blood very quickly and has the potential to spread to other body parts such as the spleen,

Acute myeloid leukemia (AML) is characterized by an increase in the number of myeloid cells in the marrow and an arrest in their maturation.(1) Make sure you use the ASM system for reference citation; I do not believe this format you have is correct. The symptoms of AML are caused by the replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells.(2) These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection.(1) Several risk factors and chromosomal abnormalities have been identified. AML progresses rapidly and is typically fatal within weeks or months if left untreated. This disease is a heterogeneous clonal disorder of haemopoietic progenitor cells.(2) These cells lose the ability to differentiate normally and to respond to normal regulators of proliferation.(2) AML has a terrible prognosis, with only 23.8% of patients surviving five years after diagnosis. (3) AML is treated initially with chemotherapy aimed at inducing a remission; patients may go on to receive additional chemotherapy or a hematopoietic stem cell transplant. The majority of patients, despite reaching complete remission with classical chemotherapy, will relapse.(3) The persistence of malignant cells is what causes remission. (3) Acute myeloid leukemia affects both older and younger patients. However, most patients are older than 60 years old, and the prognosis is worse for

Acute Myeloid Leukemia is also known to be called AML and is the most common form of all acute leukemias out there. AML is generally an older person’s disease and it is uncommon in people under the age of 45 while the average age for a person with this disease is 68 years of age. AML is much more common in men than women and the risk of both male and female being diagnosed with acute myeloid leukemia is less than half of one percent. AML is rare in the diagnosis and it is estimated for the year 2018 for new patients to be diagnosed with AML is about 19,520 this is mostly in adults. The deaths that are estimated for the year 2018 is 10,670 with AML and almost all will be adults. It is said in iMedPub Journal that adults do not participate

Having to watch a person suffer is quite difficult, but having to bear witness to the suffering of a child is downright heartbreaking. Thinking from a parent’s perspective it seems unimaginable to think that an innocent child, your child, could be diagnosed with cancer; and although it is rare for a child to develop cancer it is not impossible. Sadly, cancer is actually the leading cause of death by disease past infancy among children in the United States.

Jack woke up one morning not feeling well. He felt very weak and could not get out of bed. His mother decided to take him to the doctors. The doctors took many tests to figure out what was making him feel that way. After about an hour or two the doctors got the results back from a blood test. Results that would change Jack’s childhood for the worse. Jack has been diagnosed with Leukemia, a blood cancer. Of course, Jack was not sure what that meant but, his parents became worried beyond belief with the long road ahead of them. Scientists and researchers were all involved in the discovery of Leukemia cancer, which increased knowledge of this cancer, decreased deaths and discovered treatments, and started charity groups to fund research.