A Brief History of Antibiotics, Antibiotic Resistance, and Antibiotic Alternatives

When penicillin was released to the public in 1944, it was a miracle drug. Infections that had been killers were suddenly treatable. Doctors recommended it generously, both for illnesses that needed it and illnesses that didn’t. Before long, however, it took much stronger doses to see penicillin’s effects. When the antibiotic arms race began in 1944, most physicians assumed that new antibiotics would be discovered or created to keep up with the evolving resistance in bacteria, but the bacteria are constantly evolving new defenses and doctors are starting to run low on antibiotic ammunition. MRSA, methicillin-resistant Staphylococcus aureus, is one of many types of bacteria

The outlook on antibiotics has changed dermadicly since we have fist started using them. Antibiotics is a substance that is produced by a microorganism that can kill or prevent the growth of another microorganism. The major conflict that will be covered in the paper is antibiotic resistance. Antibiotics resistance

Farm animals receive 30 times more antibiotics (mostly penicillins and tetracyclines) than people do. The drugs treat and prevent infections. But the main reason farmers like them is that they also make cows, hogs and chickens grow faster from each pound of feed. Resistant strains emerge just as they do in humans taking antibiotics--and remain in the animal's flesh even after it winds up in the meat case. (par. 8)

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By weight, eighty percent of antibiotics are used in agriculture to “fatten animals” and “protect them from the conditions in which they are raised” (McKenna). Animals are given micro-doses of antibiotics, that is, a small amount of antibiotics to prevent diseases from occurring. This micro-dosage amount allows for mutation that Fleming described. The routine use of antibiotics in agriculture has led to “[sixty-five] percent of chicken breasts” and “[forty-four] percent of ground beef” to house bacteria “resistant to tetracycline”. Additionally, “[eleven] percent of pork chops carried bacteria resistant to five classes of drugs” (McKenna). These bacteria then spread from animals to the humans who eat them, causing humans to get infections which cannot be treated. The issue isn’t as simple as ceasing to give antibiotics to animals. Most animals raised for consumption live in an environment ripe for infections and diseases to spread. Instead of giving the animals more room to live, the majority of farmers opt to give the animals antibiotics. For cattle, This prevents diseases and death to the immature weaned calves and cattle which saves the rancher both time and money—passing on the savings to the consumers. In a free market society higher prices tend to not go well. However, if antibiotics became useless farmers would have to “[enlarge] barns, [cut] down on crowding, and [delay] weaning”, which ultimately would increase the costs of raising livestock

Antibiotics started being used for production purposes around the 1940s, farmers started to notice that when antibiotics were fed to their poultry, it promoted growth. This fast growth curve was especially liked by farmers because it increased the profits on their farms. From that point on, antibiotics were incorporated into livestock’s regular feed. In 1951, the FDA approved the first antibiotic that could be used for extra weight gain. It wasn’t until of 1969 that scientists started discovering antibiotic resistance due to the careless use by farmers. “When

Before the turn of the 21st century, physicians across the country were realizing that the possibility of being able to treat and cure virtually any microbial infection with the use of a single or a combination of antimicrobial medications was becoming more and more of a challenge. In the late 1960s and early 1970s, reports of pathogenic resistance to even the most potent antimicrobial medications of the time were being sent to the Centers for Disease Control. Among even the most dangerous pathogens that have developed and are developing drug resistance to one or many antimicrobials, Staphylococcus aureus (S. aureus) is perhaps a case in which the world is most familiar and of the greatest concern within the medical community due to its natural virulence-its ability to cause a multitude of life-threatening infections, and its above average ability to combat and adapt to a vast array of environmental conditions.

The misuse of penicillin and other antibiotics however is causing the growing problem of antibiotic resistance in which seemingly harmless infections turn to be deadly and dangerous. Antibiotics are not only casually used as treatments for bacterial infections, but are also used in agriculture and veterinary medicine, creating controversy on the proper uses of antibiotics. As advancements in the medical fields proved to be beneficial for a short period of time, today the misuse of these innovations are creating more and more problems that have proven to be dangerous to the accustomed health of the global population. Antibiotics were not always considered to be a superficial medication and, in fact, have been naturally used for millions of years, like with ants and their symbiosis with antibiotic producing fungi. Humans do not fully realize the value that antibiotics have brought to the population and do not take measures to preserve their use. In contrast, humans take for advantage the natural benefits that is given to them to overly benefit themselves, such as while creating revenue through mass production despite warning from scientists. This selfish misuse leads to consequences in which the future will have to provide solutions for, and perhaps even follow in the ants’ footsteps.

Antibiotic resistance can develop wherever antibiotics are: medical facilities, animal products and communities. Breaks in infection control, inadequate water sanitation and poor hygiene all contribute to the spread of resistant bacteria from person to person (Collignon, et al., 2015). The majority of antibiotic usage worldwide is in animals raised as a food source (Collignon, et al., 2015). 80% of antibiotic use in the United States is for growth promotion and disease prevention of farm animals used for food sources (CDC, 2015). This usage of antibiotics leads to the development of resistant bacteria, which spread to people via the food chain or water (Collignon, et al., 2015).

Prophylactic antibiotics are “using antibiotics to guard against or prevent the spread or occurrence of disease or infection.” This is a paradoxical façade presented to us by the majority of the medical world, the cattle and animal agriculture industry, and the fortune 500 companies (Prophylaxis). Prophylactic antibiotics kill tens of thousands of people every year; approximately 23,000 people from last year alone had prophylactic antibiotic related deaths, and are suspected to significantly help the progression of superbugs (Threat Report 2013). Superbugs, or antibiotic-resistant bacteria, are one of the very likely results of prophylactic antibiotics, superbugs are a quiet crisis that people of the world should be aware of, considering

In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.

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A couple times a year local and national mass media put the spotlight on problems connected to antibiotic overuse. Some people consider those problems to be real and serious, and others think that the discussed topics are nothing more than new “fashionable” subjects to talk about, distracting people from “real” problems, such as climbing gas prices or war expenses. Meanwhile, antibiotic overuse continues as a common practice among US doctors and agribusinesses for the last 20 years. The practice of antibiotic overuse has put patient’s health at risk, contributed to antibiotic resistance and increased bacterial mutation to a new, stronger level; as well as it hitting the economy with new costly expenses in health care. It is time to stop

While the United States is only experimenting with Arts based schools, countries around the world have been using Arts based curricula for years with overwhelming academic success (Oddleifson: 1989). Music instruction is described as a powerful tool that educators can use to promote academic achievement and mental discipline. As she further continues, Music is more than learning to sing and play an instrument, more than entertaining or pleasing the audience, more than a pleasant diversion or recreation. Music is a science, a mental discipline, it is an art. It has a mathematical foundation and above all it is a physical activity. (Joyce Kelstroom 98:41) As this subject is defined, it incorporates all the other disciplines that students learn at school, why then do we lack Music program in our schools?

The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be used to try and kill it and the cycle becomes vicious. Michael Martin, Sapna Thottathil, and Thomas Newman stated that antimicrobial resistance is, “an increasingly serious threat to global public health that requires action across all government sectors and society” (2409).