In a confining hospital bed back in March 1942 at New Haven Hospital, thirty-three year old Anne Miller was at the brink of death. A delirious, semi-conscious woman with a 107 degree fever suffering from streptococcal infection, there seemed to be no hope for her. Her desperate doctors tried and failed every possible treatment they could think of from sulfa drugs to blood transfusions to surgery. There was one scrap of possibility left for the survival of Anne. Her doctor coincidentally had a different patient who was friends with an Australian pathologist working on developing an experimental drug that could possibly ward off infections such as these. Rushed in from a lab in New Jersey, the experimental drug was immediately injected into Anne …show more content…
The misuse of penicillin and other antibiotics however is causing the growing problem of antibiotic resistance in which seemingly harmless infections turn to be deadly and dangerous. Antibiotics are not only casually used as treatments for bacterial infections, but are also used in agriculture and veterinary medicine, creating controversy on the proper uses of antibiotics. As advancements in the medical fields proved to be beneficial for a short period of time, today the misuse of these innovations are creating more and more problems that have proven to be dangerous to the accustomed health of the global population. Antibiotics were not always considered to be a superficial medication and, in fact, have been naturally used for millions of years, like with ants and their symbiosis with antibiotic producing fungi. Humans do not fully realize the value that antibiotics have brought to the population and do not take measures to preserve their use. In contrast, humans take for advantage the natural benefits that is given to them to overly benefit themselves, such as while creating revenue through mass production despite warning from scientists. This selfish misuse leads to consequences in which the future will have to provide solutions for, and perhaps even follow in the ants’ footsteps. …show more content…
Possible solutions for resistance in the future are to find new antibiotics in niches besides soil, such as the marine environment as globalization and deforestation make new soil discoveries harder each day. Educating people about resistance to prevent misuse is important as well because not everybody knows about the growing resistance problem. If people know about the resistance problem, proper use of antibiotics would increase. Antibiotics today are easily accessible without the need of prescription in most cases, leading to the wrong self-diagnosis based on observation instead of actual tests. Creating more regulations to ensure prescriptions and correct diagnosis will help with the misuse of antibiotics. Stopping their use as growth hormones in agriculture will also help because the antibiotics from the plants and animals are able to unnecessarily get into a person’s body, which promotes more antibiotic resistance since the dosages are not consistent. As the antibiotics pass through the livestock and people, they contaminate the water system. The antibiotic resistance today does not necessarily mean the end of antibiotics as long as
Antibiotics are inarguably one of the greatest advances in medical science of the past century. Although the first natural antibiotic Penicillin was not discovered until 1928 by Scottish biologist Alexander Flemming, evidence exists that certain plant and mold growths were used to treat infections in ancient Egypt, ancient India, and classical Greece (Forrest, 1982). In our modern world with the advent of synthetic chemistry synthetic antibiotics like Erithromycin and its derivative Azithromycin have been developed. Antibiotics have many uses including the treatment of bacterial and protozoan infection, in surgical operations and prophylactically to prevent the development of an infection. Through these applications, antibiotics have saved countless lives across the world and radically altered the field of medicine. Though a wonderful and potentially lifesaving tool, antibiotic use is not without its disadvantages. Mankind has perhaps been too lax in regulation and too liberal in application of antibiotics and growing antibiotic resistance is the price we must now pay. A recent study showed that perhaps 70% of bacterial infections acquired during hospital visits in the United States are resistant to at least one class of antibiotic (Leeb, 2004). Bacteria are not helpless and their genetic capabilities have allowed them to take advantage of society’s overuse of antibiotics, allowing them to develop
Before 1928, infections such as pneumonia and gonorrhea were untreatable, and many died of blood poisoning due to lesions that are considered minor in modern times. There were no known antibiotics that could kill the bacteria that caused such infections, so people would die of minor illnesses, such as strep throat. However, Alexander Fleming noticed something odd in one of the petri dishes at St. Mary’s Hospital in London, and this seemingly insignificant observation would revolutionize the field of medicine. He was cultivating strains of the Staphylococcus bacteria, and he found that there were not any bacteria colonies growing near a patch of mold in the dish. After looking more into this finding, Alexander Fleming learned that the mold was actually a strain of Penicillium notatum, and it had the capacity to kill malign bacteria like streptococcus, meningococcus
In this reading there was many very interesting facts about penicillin. Penicillin was a breakthrough in the medical field in the 20th century. The scientist Alexander Fleming had accidentally spilled a vile of bacteria on to a plate of bacteria to his benefit he found that is had stopped the growth of bacteria. This accidental discover has benefited everyone in the world because we have to get these shots if we are infected, plus it saved many life’s in world war II. However, Penicillin is considered an antibiotic chemical that is created by living organism to stop the growth of bacteria and prevent an illness if people were to come into contact with this problem. Since the discovery and massive stock piling of this cure it has become less
Since the introduction of penicillin to the public in 1942, antibiotics have gained widespread use throughout the world. The drug has allowed society to make advancements in medicine, increase an individual’s personal well-being, extend life expectancies, and stop and prevent infections. Antibiotics are one of the largest backbones to maintaining personal health in society today, yet there may be a day when we are no longer able to depend on antibiotics to fight infections. In the essay “Imagining the post antibiotic future”, Maryn McKenna establishes the importance of antibiotics to juxtapose how devastating life would be without them.
“Penicillin is effective in lowering mortality in gas gangrene after adequate excision of devitalized tissue, but is relatively ineffective without such supportive surgical excision. This final appraisal of penicillin therapy for gas gangrene received British and American concurrence.” Penicillin was successful in treating gas gangrene, something physicians would have said “impossible” in 1914, during The First World War. Then, the only thing doctors could do was watch their patients die as they succumbed to their infections. Now, because of penicillin, there was a way to save them, and that is why penicillin was so important. The fact that the Allies were the only ones who had access to it added to its significance. Also, the fact that the Allies tried as hard as they did to prevent Germany from getting it
As the world’s population continues to grow exponentially, the area of arable farmland shrinks. As a result, new techniques in agriculture have been developed in order to produce more food using less land. Many of these techniques are considered innovative but come at the cost of the environment or human morality. One example, the large-scale use of antibiotics in livestock feeding, has become a staple of the American agriculture industry. Of all the agricultural advancements the industry has made since the days of the horse and plow, none has been as threatening to human health as the use of sub therapeutic levels of antibiotics (Schneider). Antibiotics are useful for sick animals, just as they are useful for sick humans. In the
It seems that human can start to overcome most of diseases by using antibiotics without any bad influence. But as time goes by, the side effects show up. The excessive use of antibiotics brings the disadvantages and problems with the heaps of advantages simultaneously. Antibiotics are not only exacerbating the health risk of animals, and human beings, but also exacerbating the environmental impairment. The antibiotics are used to treat and prevent diseases in human beings and animals’ medicine, but there are many kinds of risks deriving from the antibiotics therapies, which include the development and spread of resistant bacteria strains and environmental contamination; besides, the micro-biotic organism is also a big issue we need to concern about.
Many people have died in the past due to infectious diseases. A human with an infection creates another organism which reproduces inside them. Like the pest, one of the most famous diseases killed millions of people in the 14th century. The only way to kill or stop the growth of an infection or bacteria is with antibiotics. The first antibiotic ever created was the penicillin and the greatest one till now. This drug was discovered by Alexander Fleming in the 1920´s but it was introduced in the 1940´s. Scientist began testing penicillin on lab rats but eventually, it was tested in humans. A man contracted a severe infection from a scratch on his face and Penicillin was given to him where he improved dramatically. After World War II, scientists
The war against bacteria and their ability to evolve at a much faster rate than humans can create antibiotics (a medicine that hinders and disrupts bacterial growth and or destroys it) to fight against them has the human race at a disadvantage. With more and more bacteria being found to have strains of drug-resistant chains is creating a health crisis around the world as global health officials try to find a way to protect their populations against this up and coming threat, and the issues it poses for the future of medicine and treatment of infections. Due to increased use of antibiotics in unneeded situations, bacteria are having more chances to let mutations that are immune to antibiotics be spread through other bacteria. This is causing more cases of antibiotic resistant bacteria and increasing the number of them. Drug resistance results in higher costs due to longer hospital pays and more expensive antibiotics, need for supervision, patient education, and new drug developments.
One of the greatest advances in the medical field that are within the microbiology area was the discovery of the penicillin in the 1940s by Alexander Fleming, Professor of Bacteriology at St. Mary's Hospital in London. Although the initial recognition of its therapeutic effects occurred in the United Kingdom, the United States are the ones that turned this limited substance into a widely available medicine by developing a large-scale production of this life-saving
Antibiotics came into the commercial setting in the 1940s, when penicillin began to be used to treat infections. Shortly after, livestock and poultry farmers began to integrate antibiotics into their conventional farming methods. Now, less than a hundred years later, 70% of all antibiotics that are used in human medicine are also used in agriculture and livestock, while 80% of all antibiotics in the U.S. are used in animals. Although this has increased meat and poultry production and lowered the cost for consumers, we are on a treacherous path to reversing the last 100 years of advanced medical discoveries.
The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be used to try and kill it and the cycle becomes vicious. Michael Martin, Sapna Thottathil, and Thomas Newman stated that antimicrobial resistance is, “an increasingly serious threat to global public health that requires action across all government sectors and society” (2409).
In 1928, when Dr. Alexander Fleming (Fleming, 1928) inadvertently discovered the antibacterial – penicillin, he forever changed medical history. Infections were no longer a terminal diagnosis; rather this miracle anti-microbial would decrease the period of illness and exterminate the pathogenic bacteria, thus saving many patients’ lives. But in the brief period of four years following drug companies’ mass-producing of penicillin in 1943, bacterial microbes began to show resistance to drugs (American Chemical Society, 1999).
Humans have come to rely on antibiotics for almost every illness known to man. The use of antibiotics has saved thousands of lives. However, our reliance upon antibiotics may have to come to an end because, the bacteria that we use antibiotics on have begun to evolve. This is not a mere epidemic. These are not just localized cases. This is a prevalent change all throughout the world. I can only picture two ways to overcome this attack. One way is the reduction of antibiotic use. The other method is that we need to create new and improved antibiotics to surpass the evolved bacteria. Marcelino Campos believes that, antibiotic resistance is a serious issue in which our medical systems need to find a solution (1). Understanding why antibiotic resistance
As a surgical Technologist in the Operating room, I have witnessed first hand the destruction and suffering that bacteria can have on the body. Some infections only cause minor discomfort and inflammation. Other bacteria such as streptococcus can cause horribly debilitating diseases such as Necrotizing Fasciitis1. I have also seen that bacterial resistance can play a central role in the outcome of a patient and their future life. Resistance can even determine if a person lives or dies from a bacterial infection. This is in no way more present to me than in the life of my grandmother who, through years of diabetic complications and treatment, is now left with less than a handful of antibiotics that will work to treat her conditions. Dr. Keiji Fukuda of the World Health Organization said it best, “Without urgent, coordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and minor injuries which have been treatable for decades can once again kill.”2 With how many people that have infections today, the topic of antibiotics is of utmost importance. The aim of this paper is to look at the history of antibiotics, how they work and why they are not working now, and the possibility of better antibiotics in our future.