T-cell receptor diversity is controlled by __________. Select one: a. DNA recombination during prophase of meiosis I b. DNA recombination during prophase of meiosis II c. DNA recombination during mitosis in T-cells d. proteasomal degradation of host proteins e. proteasomal degradation of viral proteins
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- T-cell receptor diversity is controlled by __________ a. DNA recombination during prophase of meiosis II b. proteasomal degradation of host proteins c. proteasomal degradation of viral proteins d. DNA recombination during mitosis in T-cells e. DNA recombination during prophase of meiosis IT-cell receptor diversity is controlled by Select one: DNA recombination during prophase of meiosis | O b. DNA recombination during prophase of meiosis II O C. DNA recombination during mitosis in T-cells O d. proteasomal degradation of host proteins proteasomal degradation of viral proteinsT-cell receptor diversity is controlled by O b. O c. 1 O d. e. DNA recombination during mitosis in T-cells DNA recombination during prophase of meiosis II DNA recombination during prophase of meiosis l proteasomal degradation of viral proteins proteasomal degradation of host proteins
- The head of the oncology divison of a large biotech company proposes to develop a therapeutic antibody to treat cancers with mutant B-Raf oncogene. Is this a good idea? Why or why not(limit 3-4 sentences)?Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous chromosomes a. die by apoptosis in the bone marrow b. will rearrange heavy-chain loci multiple times until a productive rearrangement is made c. undergo clonal proliferation d. upregulate expression of transcription factors E2A and EBF e. fail to rearrange V to DJ.In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by follicular dendritic cells in the germinal center. other B cells in the germinal center. TFH cells in the germinal center. any CD4 T cell in the same lymph node. 00
- _______ involves successive rearrangement at the lightchain loci when reactivity to self antigen occurs during B-cell development. a. receptor editing b. somatic hypermutation c. chromosomal translocation d. clonal deletion e. anergy.Order the listed proteins in the correct order so that cell proliferation is activated as the endpoint. 1. ERK1/2 2. MEK1/2 3. a MAPKKK 4. hepatocyte growth factor 5. c-MET 6. a GEF 7. RasAll of the following regarding CD1a, b, and c are true except _____. a. They have a more limited tissue distribution than CD1d. b. CD1b associates with CD1e for the purpose of lipid transfer. c. They cycle through endosomal vesicles in different locations of the cell with the assistance of adaptor proteins. d. They possess different sizes of antigen-binding sites. e. They all present lipid antigens. f. They cycle continually between the cell surface and endosomal compartments, allowing exchange of antigens. g. CD1b can accommodate more than one antigen simultaneously. h. They are expressed by double-positive thymocytes and facilitate positive selection of CD1-restricted T cells. i. They present antigens to NKT cells.
- Barriers to using pig organs in human transplantation are _____. (Select all that apply.) a. the transfer of endogenous pig retroviruses to humans b. that pig organs secrete high levels of cytokines that induce inflammation in humans c. that humans contain preexisting alloantibodies that bind to pig carbohydrate antigens on pig endothelium d. that pig MHC molecules stimulate strong xenoreactive T-cell responses e. that pig complement regulatory proteins do not inhibit human complement.E DBOW GENERAL-BIOLOGY-1.ec x A genbio1_mod2_-Cell-Types and x O File | C/Users/Acer/Desktop/genbio1/genbio1_mod2_-Cell-Types%20and%20Cell%20Modifications%20(1).pdf ... D Page view | A Read aloud V Draw E Highlight 12 of 20 Erase What are nervous tissues? How does the nervous tissue work? What makes up a typical nerve cell or neuron? Dendrite Cell body Axon Nervous tissue senses stimuli and transmits signals called nerve impulses from one part of an animal to another. It has a cell body, containing the cell's nucleus, and several slender extensions. One type of extension, called a dendrite, conveys signals from its tip toward the rest of the neuron; another type, the axon, transmits signals toward another neuron or to a muscle cell. What's More Helow is a picture that showa the organs of a human torso. Identify the tissue that ia found in each labeled part of the torso. Inger HUure: VeciurSuk File name: Human anatomy model with different aystems Vector Image 9 10:32 am P Type here to…B cell receptor diversity is behind our ability to fight new infections. However, epitope-specific B Cell memory is critical for the secondary immune response protecting against new infections. You are ready to integrate concepts. In this question, you will combine B Cell receptor diversity and cloning! Please answer each question in less than 150 characters (including spaces). 1.Can a mature B Cell produce an epitope-specific antibody first and then switch to make an antibody against a different epitope? Explain. 2.Please describe what is transferred into an egg during cloning by somatic nuclear cell transfer. 3.How many B Cell receptors/antibodies could be generated in a mouse cloned by somatic nuclear cell transfer from a mature B Cell (after recombination)?