Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous chromosomes a. die by apoptosis in the bone marrow b. will rearrange heavy-chain loci multiple times until a productive rearrangement is made c. undergo clonal proliferation d. upregulate expression of transcription factors E2A and EBF e. fail to rearrange V to DJ.
Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous chromosomes a. die by apoptosis in the bone marrow b. will rearrange heavy-chain loci multiple times until a productive rearrangement is made c. undergo clonal proliferation d. upregulate expression of transcription factors E2A and EBF e. fail to rearrange V to DJ.
Concepts of Biology
1st Edition
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter17: The Immune System And Disease
Section: Chapter Questions
Problem 3ACQ: Figure 17.17 The Rh antigen is found on Rh-positive red blood cells. An Rh-negative female can...
Related questions
Question
Developing B cells that fail to make productive D to J heavy-chain rearrangements on both homologous chromosomes |
a. die by apoptosis in the bone marrow |
b. will rearrange heavy-chain loci multiple times until a |
productive rearrangement is made |
c. undergo clonal proliferation |
d. upregulate expression of transcription factors E2A and EBF |
e. fail to rearrange V to DJ. |
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 4 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Concepts of Biology
Biology
ISBN:
9781938168116
Author:
Samantha Fowler, Rebecca Roush, James Wise
Publisher:
OpenStax College
Concepts of Biology
Biology
ISBN:
9781938168116
Author:
Samantha Fowler, Rebecca Roush, James Wise
Publisher:
OpenStax College