QUESTION 1The Wnt signaling pathway component, Dsh, effects the action of B catenin by:O A. inhibiting the function of axin in the destruction complexO B. blocking GSK-3B from joining the destruction complexO C. stimulating ubiquitination of B cateninO D. causing its release into the cytosol from the plasSma membrane complexO E. causing an increase in phophorylation of B cateninQUESTION 2PCR can be used to identify the breakage points of mtDNA that are joined to forma mitochondrial genome with a deletion.This technique uses:O A. two primers outside the deleted region; a long PCR extension segment.O B. one primer within the deleted region and one primer outside the deleted region; a long PCR extension segmentO C. one primer within the deleted region and one primer outside the deleted region; a short PCR extension segmentO D. two primers outside the deleted region; a short PCR extension segmentO E. two primers within the deleted region; a short PCR extension segment

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QUESTION 1 The Wnt signaling pathway component, Dsh, effects the action of B catenin by: O A. inhibiting the function of axin in the destruction complex O B. blocking GSK-3B from joining the destruction complex OC. stimulating ubiquitination of B catenin O D. causing its release into the cytosol from the plasma membrane complex O E. causing an increase in phophorylation of B catenin

QUESTION 1 The Wnt signaling pathway component, Dsh, effects the action of B catenin by: O A. inhibiting the function of axin in the destruction complex O B. blocking GSK-3B from joining the destruction complex OC. stimulating ubiquitination of B catenin O D. causing its release into the cytosol from the plasma membrane complex O E. causing an increase in phophorylation of B catenin

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 12RQ: Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway...

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QUESTION 1 The Wnt signaling pathway component, Dsh, effects the action of B catenin by: O A. inhibiting the function of axin in the destruction complex O B. blocking GSK-3B from joining the destruction complex O C. stimulating ubiquitination of B catenin O D. causing its release into the cytosol from the plasma membrane complex O E. causing an increase in phophorylation of B catenin QUESTION 2 PCR can be used to identify the breakage points of mtDNA that are joined to form a mitochondrial genome with a deletion. This techni que uses: O A. two primers outside the deleted region; a long PCR extension segment. O B. one primer within the deleted region and one primer outside the deleted region; a long PCR extension segment O C. one primer within the deleted region and one primer outside the deleted region; a short PCR extension segment O D. two primers outside the deleted region; a short PCR extension segment O E. two primers within the deleted region; a short PCR extension segment
Question 12 Match the tenzyme with the post translational moidification v pyruvate detydrogenase complex a. lipoylysine v aconitase b. phosphotylation an serine v phosphoglycerate mutase c ron-sultur center v phosphoglucomutese d. phosphorylation an histidine A Moving to another question will save this response.
Question 25 What is the direct result of membrane depolarization in the release of insulin from pancreatic islet of Langerhans ß cells? A. Increased intracellular Ca ⒸB. Reduced ATP synthesis C. The incretin effect OD. Increased glycolysis OE. B cell apoptosis
Question 9. What triggers the entry of a cell into mitosis? A. the addition of inhibitory phosphate groups to Cdk1 by the Cdc25 phosphatase B. the addition of inhibitory phosphate groups to Cdk1 by the Wee1 kinase C. the removal of inhibitory phosphate groups from Cdk1 by the Wee1 kinase D. The addition of an activating phorophorylation to Cdk1 by the Cdc25 phosphatase E. the removal of inhibitory phosphate groups from Cdk1 by the Cdc25 phosphatase Short Answer
Question 12 Identify the key step in regulation of protein hormone release. O A. Exocytosis B. Signal sequence cleavage O C. Diffusion through the cell membrane D. Kinase activation of biosynthetic enzymes E. Golgi transport
Question 13 Which of the following is a property of signaling for epinephrine, growth hormone, GIP and somatostatin? A. Conversion to an active form in the target tissue OB. Cell surface receptor binding OC. Diffusion into the cell nucleus OD. Inhibition of a tyrosine kinase O E. Activation of transcription
Question 5. Which of the following statements regarding G-protein coupled receptors (GPCRs) is true? A. The GPCR is a tyrosine kinase. B. The trimeric G-protein becomes inactivated upon binding to the GPCR. C. The GPCR functions as a dimer. D. The GPCR associates with a trimeric G-protein. E. The GPCR is activated without binding to ligand. A B Multiple Choice C D E
Question 24 Which of the following is not a cell surface receptor? GPCR ODNA-associated receptor RTK TNF receptor Question 26 Somatic recombination and hypermutation adds to the diversity of Ig's O True False Question 27 GPCRs interact with heterotrimeric G proteins composed of a, ß, and y subunits that are GTP bound in the resting state. O True False
Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway constriction associated with an allergic response. If a mutation in the associated G-protein’s alpha subunit prevented the hydrolysis of GTP how would the allergic response change? More severe allergic response compared to normal G-protein signaling. Less severe allergic response compared to normal G-protein signaling. No allergic response. No change compared to normal G-protein signaling.
Question 4. Which of the following statements are true of tyrosine kinases? A. They always bind to a dimeric ligand. B. They trans-autophosphorylate themselves in their cytoplasmic domain. C. They must be associated with a G-protein to function. D. They contain seven membrane-spanning domains. E. They always activate a transcription factor. A B Multiple Choice C D E
Question 21 Which effect is a response to glucagon secretion? O A. Inhibition of skeletal muscle VLDL transport O B. Activation of skeletal muscle glycogenolysis C. Inhibition of liver tyrosine phosphatase D. Activation of adipose hormone sensitive lipase O E. Activation of liver GLUT2
Question 31 Select the example of juxtacrine signaling. O Cell signals itself O Cell signals via direct contact with another cell O Cell signal local area cells Cell signals to targets throughout an entire body « Previous