Do not give handwriting solution Blood plasma contains a total carbonate pool (essentially HCO3 and CO₂(d)) of 2.5x 10-2 M. What would be the pH if 12 mM H+ is added under conditions where theincreased [CO₂(d)] can be released (i.e., an open system)? Assume the normal pH(i.e., before addition of H*) is 7.40. Recall that the pKnet for the net reaction in whichwater plus dissolved carbon dioxide form hydrogen ions plus bicarbonate ions is 6.1.Enter your answer to the nearest hundredth.

In order to solve this problem, first we need to calculate the initial concentrations of bicarbonate…

Answered: Blood plasma contains a total carbonate…

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter11: The Blood

Section: Chapter Questions

Problem 1SQE

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Blood pH is maintained at a range of 7.4. The following set of equations representsthe reactions of the blood buffering system. The pk, for the dissociation ofH,COg into HOg and H* is 6.3.Carbonic AnhydraseCO2 + H2OH2CO3> HCO3- + H+(a) (Calculate the ratio [HCO3 ]/[H,COg] at physiological pH. Show work.(b)) An individual with diabetes presented at an urgent care with fatigue andnausea. Lab tests showed that their blood [HOg ]/[H,COg] ratio was 3.4. Whatwas the pH of the patient's blood? Show work.(c) ) Clinic staff also noticed that the patient was breathing rapidly. What isthe reason for this rapid breathing and how might it help alleviate the patient'scondition?
Acetazolamide is a carbonic anhydrase inhibitor that is used to treat glaucoma. It has two acidic groups and has 2 pKb’s as shown below: What is the concentration of dihydrogen acetazolamide (BH22+) in a 0.5000 M solution of acetazolamide (B)? What is the concentration of hydronium ion (H+) in a 0.5000 M solution of acetazolamide (B)?
Calculate the actual free energy of hydrolysis of ATP, delta Gp in the erythrocytes of a new species. The standard free-energy of hydrolysis of ATP is also -30.5kJ/mol in this species, but the concentrations in this specie's erythrocytes are 0.00760 mM ATP, 0.00063 mM ADP and 0.00273 mM Pi. Assume the pH is 7.0 and the body temperature of this species is 91.0oC. Calculate your answer as kJ/mol to two decimal places.
Acetazolamide is a carbonic anhydrase inhibitor that is used to treat glaucoma. It has two acidic groups and has 2 pKb’s as shown below: What is the concentration of acetazolamide (B), in a 0.5000 M solution of acetazolamide (B)? What is the concentration of hydrogen acetazolamide (BH+) in a 0.5000 M solution of acetazolamide (B)?
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If we were handed a tuke of 2mg/mL BSA how much is required 20μL of each of the following Concentrations? to make zoul total bring up to volume with dH ₂0 @ 01125 mg/mL (1) 0,150 mg Ⓒ 0.50 mg/mL @ 0.75 mg/mL Ⓒ 1.0mg/ml /ML Can it be solved using C₂ C₁V₁ = C₂ V₂ If CI= V₁ yes, please show work. Vz
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On the right the Hill plot com- (b) pares the O2 binding properties of Hb Ya- kima with those of HbA in 0.1 M NaCl buff- Hb-Yakima ered to pH 7 with 0.01 M bis-Tris. Focus first on the line for "stripped Hb". This is the term for hemoglobin isolated from erythro- cytes with removal of all organic phosphate molecules that might bind to the protein in RBCS. You can see that 2,3-bisphospho- glycerate (BPG; labeled DPG according to old terminology) does not alter the O2 bind- ing affinity of Hb Yakima in contrast to HbA (although it was shown that BPG did bind to the deoxyHb Yakima molecule). Also, Hb Yakima is associated with markedly decreased allostery in the absence and presence of BPG, in comparison to HbA. IHP = inositol hexaphosphate, an artificial allosteric modifying ligand that binds more tightly than BPG. stripped Hb Hb-A •DPG +DPG n= 1.0 n = 2.3 n=2,5 +THP +IHP 0.5 0.5 1 5 10 50 po, ( mm Hg ) %3D On the right is a diagram copied from the lecture handout "Hemoglobin and Allo-…
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Paclitaxel is used to treat ovarian cancer by infusion at a concentration of 0.6 mg/mL over 24 hours. A dose of 135 mg/m² has been prescribed for Sero. Sero is 1.06 m tall and weighs 92 kg. Paclitaxel comes in vials of 150 mg/25 mL. Calculate the volume of 5%w/v glucose solution that would be required to dilute the concentrated solution to prepare an paclitaxel solution of the required strength. Answer: You did not give the correct unit. The correct answer is: 333 mL X

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