Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 42, Problem 14TYK
Summary Introduction
To review:
An experiment to observe whether a new synthetic chemical is an endocrine disruptor.
Introduction:
The endocrine disruptors can be defined as the chemical substances that interfere with the activity of hormones at some specific dose. As a consequence of their activity, cancerous tumors, developmental disorders, and birth defects takes place. The endocrine disruptors derail the functions controlled by the hormones in the body.
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Place the following steps (showing how a steroid hormone changes the activities of its target cells) in order of what happens first, second, third, fourth, and last. Refer to image.
The hormone-receptor complex enters the nucleus of the cell and binds to the DNA.
The steroid hormone passes through the cell membrane.
The hormone attaches to a receptor in the cytoplasm, forming a hormone-receptor complex.
A gene in the DNA is activated, and transcription and translation take place.
Proteins that alter the cell′s activities, such as enzymes, are made.
2. Place the following steps (showing how a hydrophilic hormone changes the activities of its target cells) in order of what happens first, second, third, and last. Refer to image.
The activity of the target cell is changed by the final enzyme in the cascade.
The second messenger activates or deactivates certain enzymes in a cascade fashion.
A second messenger is activated.
Hormone binds to a receptor protein.
Which of the statements is/are incorrect for hormones?
1) Hormones are non-nutrient chemicals serving as intercellular messengers.
2) Hormones are molecules of low molecular weight and are produced in traces.
3) Hormones give energy and also effect metabolism and growth activities of target cells.
4) Many hormones are produced in inactive form.
How could the origin of endocrine control systems lie in ordinary cellular events? How might the earliest multicellular organisms have evolved some sort of endocrine coordination?
Chapter 42 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 42.1 - What is the difference between a hormone and an...Ch. 42.1 - How is endocrine signaling different from...Ch. 42.2 - Prob. 1SBCh. 42.2 - Prob. 2SBCh. 42.3 - Prob. 1SBCh. 42.3 - Prob. 2SBCh. 42.4 - What effect does parathyroid hormone have on the...Ch. 42.4 - Prob. 2SBCh. 42.4 - Prob. 3SBCh. 42.4 - Prob. 4SB
Ch. 42.5 - How do hormones compare structurally and...Ch. 42 - Prob. 1TYKCh. 42 - Prob. 2TYKCh. 42 - When the concentration of thyroid hormone in the...Ch. 42 - Which of the following statements about endocrine...Ch. 42 - Prob. 5TYKCh. 42 - Prob. 6TYKCh. 42 - If the human body is stressed, glucocorticoids: a....Ch. 42 - Prob. 8TYKCh. 42 - Prob. 9TYKCh. 42 - Prob. 10TYKCh. 42 - Prob. 11TYKCh. 42 - Prob. 12TYKCh. 42 - Discuss Concepts In integrated pest management, a...Ch. 42 - Prob. 14TYKCh. 42 - Prob. 15TYKCh. 42 - Prob. 1ITDCh. 42 - Prob. 2ITDCh. 42 - Prob. 3ITDCh. 42 - Researchers measured prolactin and growth hormone...
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- Explain how the chemical nature of the plasma membrane acts on the two chemical categories of hormones, and thus the type of response each hormone can induce in a target cell. Be sure to thoroughly describe the two types of cellular responses.arrow_forwardUnder in vivo conditions, chronic treatment with a noncompetitive antagonist may lead to the up-regulation of the targeted receptor over time. True False Cytokines are peptides that are generally made in advance by specific types of cells, stored in vesicles, and act as autocrine or paracrine factors. True False Thyroid hormone is stored in an extracellular compartment. True Falsearrow_forwardThe binding of small amounts of hormones to target cell receptors triggers an intricate signal cascade. Why is the signal cascade necessary? Why not just have a simple molecularmechanism between the hormone and cellular effect?arrow_forward
- Identify the incorrect statement: O A. Steroid hormones, such as testosterone, are derived from cholesterol and regulate cell function by influencing transcription. O B. Melatonin is a hydrophobic steroid hormone synthesized by the pineal gland It regulates the circadian rhythm of the cell OC. Catecholamines are hydrophilic hormones synthesized from tyrosine. Therefore, membranes are barriers to them, and their receptors need to be on the extracellular surface. O D. Antidiuretic hormone is a peptide hormone that regulates fluid balance in the body O E. Thyroid hormone is a hydrophobic tyrosine derived hormone that regulates the metabolism,arrow_forwardWhich of the following is not a true statement? A.) steroid and thyroid hormone signaling would be impaired if the plasma level of carrier proteins is not optimal. B.) Steroid and thyroid hormone-receptor complexes form dimers when they bind to the hormone-response elements on DNA C.) Epinephrine uses the adenylate cyclase and the phospholipase C second messenger systems D.) signaling by a peptide hormone would be impaired if a second messenger system is not functional in the target cell E.) signaling by a steroid hormone would be hindered if the adenylated cyclase second messenger system is not functional in the target cell.arrow_forwardDistinguish between the genomic and nongenomic actions of steroid hormones. Which mechanism of action would be inhibited by a drug that interfered with protein synthesis? Explain.arrow_forward
- Signals carried by hormones must eventually be terminated. Describe several different mechanisms for signal termination.arrow_forwardExplain how mutations in the following proteins might result in either loss of responsiveness to a given hormone or production of a continuous signal even in the absence of the hormone: a mutation in a growth factor receptor with protein kinase activityarrow_forwardIn their mechanism of action, a difference between steroid and nonsteroid hormones is that __________. nonsteroid hormones bind to DNA steroid hormones enter the nucleus of the target cell, and nonsteroid hormones do not nonsteroid hormones cross the plasma membrane more readily than do steroid hormones steroid hormones use a signal transduction pathwayarrow_forward
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