To propose a mechanisms of porphobilinogen synthesis are sequenced from 5-aminolevulinate c 2 molecules.

Question

Chlorophyll, heme, vitamin B12, and a host of other substances are synthesized from porphobilinogen, which is itself formed from the condensation of two molecules of 5-aminolevulinate. The two 5-aminolevulinates are bound to lysine (Lys) residues in the enzyme, one in the enamine form and the other in the imine form. Condensation is thought to occur via a several step process, one of which is shown below. ÇO2 ÇO2 CO2 + NH3 NH3 H H3N 5-aminolevulinate (enamine form) 5-aminolevulinate (imine form) Porphobilinogen Draw curved arrows to illustrate the movement of electrons in this step of the reaction. Arrow-pushing Instructions CO2 CO2 CO2 CO2 :B BH* H-A H3N H3Ņ

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Chapter 24.SE, Problem 38MP

Interpretation Introduction

Interpretation:

To propose a mechanisms of porphobilinogen synthesis are sequenced from 5-aminolevulinate c₂ molecules.

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Chlorophyll, heme, vitamin B12, and a host of other substances are synthesized from porphobilinogen, which is itself formed from the condensation of two molecules of 5-aminolevulinate. The two 5-aminolevulinates are bound to lysine (Lys) residues in the enzyme, one in the enamine form and the other in the imine form. Condensation is thought to occur via a several step process, one of which is shown below. ÇO2 ÇO2 CO2 + NH3 NH3 H H3N 5-aminolevulinate (enamine form) 5-aminolevulinate (imine form) Porphobilinogen Draw curved arrows to illustrate the movement of electrons in this step of the reaction. Arrow-pushing Instructions CO2 CO2 CO2 CO2 :B BH* H-A H3N H3Ņ

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