Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 15, Problem 15Q
What type of diagnostic method do you think would be most suited to determining if a bacterium causing a human infection was lysogenized by a bacteriophage that contains a virulence gene?
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Chapter 15 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 15.1 - Prob. 1AYPCh. 15.1 - Provide a one-sentence description for each of...Ch. 15.2 - Identify factors that may affect the...Ch. 15.2 - Prob. 4AYPCh. 15.2 - NCLEX PREX 1. An RN is training a new staff nurse...Ch. 15.2 - NCLEX PREX 2. A clinical form used to report data...Ch. 15.3 - List at least three different tests that fall in...Ch. 15.3 - Prob. 6AYPCh. 15.3 - Discuss two major drawbacks of phenotypic testing...Ch. 15.3 - Q. What technique in this chapter do most home...
Ch. 15.3 - NCLEX PREX 3. When determining the clinical...Ch. 15.4 - Define the term serology, and explain the...Ch. 15.4 - Identify two immunological diagnostic techniques...Ch. 15.4 - Prob. 2MMCh. 15.5 - Explain why PCR is useful for infectious disease...Ch. 15.5 - Name two examples of techniques that employ...Ch. 15.5 - Explain how whole-genome sequencing can be used...Ch. 15.5 - Prob. 13AYPCh. 15.5 - Prob. 3MMCh. 15.6 - Describe the benefits of lab on a chip...Ch. 15.6 - Prob. 15AYPCh. 15 - When using pulsed-field gel electrophoresis,...Ch. 15 - Explain why it is possible to identify some...Ch. 15 - Serotyping identifies distinct members of the same...Ch. 15 - Prob. 4QCh. 15 - Name some bacterial structures that might be...Ch. 15 - You perform a lumbar puncture on a patient with...Ch. 15 - Which category of diagnosis is represented by...Ch. 15 - Write a paragraph that explains the mycobacterial...Ch. 15 - You inoculated a biochemical test strip with a...Ch. 15 - Prob. 10QCh. 15 - You perform a Kirby-Bauer disk diffusion test to...Ch. 15 - Why might culture conditions affect the results of...Ch. 15 - Which of the following techniques is most likely...Ch. 15 - Why is it more important to use selective media...Ch. 15 - What type of diagnostic method do you think would...Ch. 15 - T or F: Bacterial infection causes the expression...Ch. 15 - Prob. 17QCh. 15 - Prob. 18QCh. 15 - Prob. 19QCh. 15 - When PCR is performed by hand (not with a...Ch. 15 - What kind of a control would be important to run...
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- The following are the limitations of Koch's postulates EXCEPT: A. some pathogens cannot grow on artificial media and therefore cannot be identified as the causative agent of the disease B. some diseases involve multiple pathogens which produce similar symptoms making it difficult to pinpoint the causative agent C. some diseases are host-specific and re-inoculation may pose ethical concerns D. some microorganisms are present in the body fluids of the infected animal which make them difficult to be culturedarrow_forwardRobert Koch developed a set of criteria (postulates) for conclusively demonstrating the aetiology (specific cause) of an infectious disease. Which of the following is not a postulate? The infectious agent must be isolated and cultured in vitro The disease is reproduced when a pure culture of the infectious agent is inoculated into a new susceptible host The infectious agent can be recovered from the experimentally-infected host The infectious agent is present in most cases of the diseasearrow_forward1) What is NDM-1? How can NDM-1 spread to different types of bacteria? 2) Why are Gram negative bacteria so much harder to treat with antibiotics? 3) What is KPC? Where does it live?arrow_forward
- Which of the following is TRUE when one assay bacteriophage titers? You should: a) first mix the phages with a live bacterial culture and then pour the mixture on the agar plate b) directly add the phage dilution onto the surface of an agar plate c) add tryptic soy broth to the phage dilution and incubate overnight d) incubate a phage solution with live bacterial cells for several minutes. You must add soft agar to the mixture before pouring the content on the agar platearrow_forwardIn terms of microbial pathogenicity, molecular Koch's postulates are a set of experimental criteria that show: A microbe is the aetiological agent of a disease A gene encodes a product that contributes to disease A gene encodes a product that contributes to immunity to a disease A mutation does not contribute to diseasearrow_forward1) In 2005 a typhoid outbreak in Delmas, South Africa, prompted the widespread testing of food and water sources to ascertain the origin of the outbreak. However, the origin of the outbreak could not be definitely tracesd. What could have been the possible reasons for this state of affairs? 2) A hypothetical culture media is being developed for the isolation of Salmonella Typhimurium. How will these unique characteristics be used to produce a culture media that is both selective and differential for the isolation of presumptive Salmonella Typhimurium?arrow_forward
- Select all of the following that applies to the tradeoff between transmission and virulence that applies to many diseases. a) The tradeoff between transmission and virulence means that diseases always evolve to become more virulent. b) If greater virulence limits transmission, that disease will likely evolve to become less virulent than it could be. c) While making more copies of itself can increase the likelihood of transmission occurring, too much replication of the disease can make the host so sick it won't leave the house and spread the disease. d) A strain of a disease that replicates enough to be transmitted, but not so much that the host gets too sick to move, will be favored by natural selection over strains that either make the host too sick or do not replicate enough to be transmitted. e) If a disease can spread without making its host sick (e.g. when the host is asymptomatic), then the tradeoff between transmission and virulence…arrow_forwardQ3) More than a century ago, Robert Koch realized that to prove the germ theory of disease, he would have to develop a standard for determining causation that would stand the test of scientific scrutiny. (a) Discuss how the principles of Robert Koch's postulate play an important role in modern epidemiology. (b) Explain how an asymptomatic patient can infect another person to the point of causing the person to experience acute symptoms and possibly death.arrow_forwardWhich of the statements about bacteriophage is FALSE: a) specialized transduction is a low frequency event b) may accidently package host DNA into a phage particle c) may perform specialized transduction d) only have a lytic life cyclearrow_forward
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