Biology: Life on Earth
10th Edition
ISBN: 9780321729712
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: Benjamin Cummings
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Textbook Question
Chapter 10, Problem 5RQ
In the pedigree of part (a) of Figure 11–22, do you think that the individuals showing the trait are homozygous or heterozygous? How can you tell from the pedigree?
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The pedigree below shows a family with a history of an autosomal recessive genetic
disease with one individual's genotype indicated (G denotes the normal allele and g
denotes the disease-causing allele).
*
O 0
O 1/8
1/4
O 1/16
Individual 1's father is known to be heterozygous (*) and his mother is known to be
homozygous dominant. Other individuals in the pedigree may be carriers, but are not
marked. The question mark (?) indicates that you do not yet know anything about this
individual's phenotype with regard to the disease.
Part 1
What is the probability that individuals 1 and 2 will have a child (5) who is a male with the
disease (the child is unborn and the sex is not yet known)?
O 1/4
1
O 1/6
5
1/8
2
01/12
gg
3
Part 2
What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the
disease?
6
For this pedigree, give the most likely mode of inheritance, assuming that the trait is rare.
For the pedigree, what is the probability that III-4 and III-5 will have a boy AND he will be affected?
*Cystic fibrosis is a rare autosomal recessive condition. phenotypically normal man whose
father had cystic fibrosis marries a phenotypically normal woman from outside the family.²
a) Draw the pedigree as far as described.
b) If the frequency of heterozygotes in the general population is 1/50, what is the
probability that the couple's first child will have cystic fibrosis?
c) If the first child does have cystic fibrosis, what is the probability that the second child
will be normal?
Chapter 10 Solutions
Biology: Life on Earth
Ch. 10 - Fill-in-the-Blank The physical position of a gene...Ch. 10 - Define nondisjunction, and describe common...Ch. 10 - In certain cattle, hair color can be red...Ch. 10 - Prob. 2GPCh. 10 - In the edible pea, tall (T) is dominant to short...Ch. 10 - In tomatoes, round fruit (R) is dominant to long...Ch. 10 - In the tomatoes of Problem 4, an F1 offspring...Ch. 10 - Prob. 6GPCh. 10 - In humans, one of the genes determining color...Ch. 10 - In the couple described in Problem 7, the woman...
Ch. 10 - An organism is described as Rr, with red coloring....Ch. 10 - 2. The inheritance of multiple traits depends on...Ch. 10 - Fill-in-the-Blank Many organisms, including...Ch. 10 - 4. Genes that are present on one sex chromosome...Ch. 10 - 5. When the phenotype of heterozygotes is...Ch. 10 - 1. Define the following terms: gene, allele,...Ch. 10 - 2. Explain why genes located on the same...Ch. 10 - 3. Define polygenic inheritance. Why does...Ch. 10 - What is sex linkage? In mammals, which sex would...Ch. 10 - What is the difference between a phenotype and a...Ch. 10 - 6. In the pedigree of part (a) of Figure 11–22, do...Ch. 10 - Sometimes the term gene is used rather casually....Ch. 10 - In an alternate universe, all the genes in all...Ch. 10 - Prob. 3AC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The following family pedigree shows individuals afflicted with a metabolic disease. Suppose the male (b) and the female (c) have 2 girls and 2 boys, indicate directly on the pedigree the symbols for these children that would be most consistent with the mode of inheritance observations in the pedigree? II II a b d e IVarrow_forwardIn pedigrees, individuals are usually specified by using a Roman numeral for their generation in the chart and an Arabic number for their position (reading left to right) within that generation. If we use the letter c for the allele that causes cystic fibrosis, what are the genotypes of individuals III-3 and III-4 (the third and fourth individuals shown in generation III) in the pedigree that shows this disease?arrow_forwardThis is a pedigree for a dominant trait caused by gene A in humans. Shaded symbols show individuals affected with the trait; non-shaded individuals are normal (aa). Among the progeny arising from the marriage of individual III-1, what proportion would be expected to show the trait? Among the progeny arising from the marriage of individual III-6, what proportion would be expected to show the trait?arrow_forward
- The pedigree below tracks the inheritance of a genetic disorder through a family's generation. Determine the probable inheritance mode for the trait shown in the affected individual (the shaded symbols) by answering the following questions. I II 2 3 4 5 7 III 2 3 6 7 8 5 (i) Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your reason. (ii) What TWO (2) other modes of inheritance can be definitely excluded? Explain your answer. Of the remaining modes of inheritance, which is the most likely? Which is less likely? Explain your answers. (ii)arrow_forwardGiven the following pedigree: Is the trait autosomal or sex-linked? Is the trait dominant or recessive? Based only on the information given, what is the probability that I-2 is heterozygous? Give the genotypes of individuals II-3, II-4. What is the probability that individual III-1 is purebreeding?arrow_forwardThe three genes X, Y, and Z are linked on an autosomal chromosome in humans (X to Y is 15 cM, and Y to Z is 18 cM). If an individual that is heterozygous at all three loci (XYZ/xyz) has children with an individual that is homozygous recessive at all three loci (xyz/xyz), what is the probability that they will have a child that is phenotypically identical to either parent (X-Y-Z- or xxyyzz)? Assume there is no genetic interference to double crossover events at this site.arrow_forward
- In the below pedigree, what is the probability that the individual in generation V (marked as a "?") will have the mutant phenotype? (Assume that the mutant phenotype manifests during childhood and individual III-6 is homozygous). Enter your answer as a fraction without spaces (e.g. 9/16)arrow_forwardIn each of the following pedigrees (A, B) by inspection, determine the mode of inheritance involved. Indicate the possible genotypes of all individuals in all the pedigrees.arrow_forwardDefine the pedigree symbol(s) associated with each of the following individuals. Please be as specific as possible. Be sure to indicate WHOSE pedigree symbols you are defining. (i) II-1 and II-3 (ii) II-5 (iii) II-9-10 (iv) II-11 (v) IV-14 and IV-15 (vi) IV-18arrow_forward
- For the following cross, show the P generation Genotypes and the Phenotypic ratio that would be seen in the F1 and F2. Remember, to produce the F2 generation you want to cross Heterozygotes from the F1. d) Genes 1 and 2 exhibit Epistasis (9:6:1) and Gene 3 is an Autosomal Dominant. In the P generation, the Male is Homozygous Recessive for the Genes showing Epistasis. Use E1, E2 and E3 to represent the Phenotypes shown by Epistasis. Report your results in the following format: P = aabb x AABB, F1 = 100%AaBb (Phenotype), and %3! F2 = 9/16 A_B_ (Phenotype), 3/16 aaB (Phenotype), 3/16 A_bb (Phenotype), 1/16 aabb (Phenotype)arrow_forwardThe accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information. 1) What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AAAA and two of them are AaAa? (Hint: Consider all possible orders of genotypes.) Express your answer to two decimal places.arrow_forwardThe following pedigree shows the incidence of ABO blood types in a family. Which individual(s) is/are a known homozygote for blood type? What is/are the possible genotype(s) of individual III-2? What is/are the possible genotype(s) of individual III-3?arrow_forward
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