What would be a likely consequence if step 4 of the citric acid cycle no longer operated far from equilibrium, and instead occurred near equilibrium? the step would need to be coupled to ATP hydrolysis none of these possibilities are likely this step would no longer be a highly regulated step the reaction would no longer occur

What would be a likely consequence if step 4 of the citric acid cycle no longer operated far from equilibrium, and instead occurred near equilibrium? the step would need to be coupled to ATP hydrolysis none of these possibilities are likely this step would no longer be a highly regulated step the reaction would no longer occur

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 21P: Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and...

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The primary purpose of the aconitase step in Citric Acid Cycle is to: form the intermediate aconitate prepare the citrate molecule for oxidative decarboxylation act as a commitment and regulatory step produce isocitrate
Acetyi CoA Oxaloncetate CoA NADH NAD: Citrate Isccitrate Malate NAD co NADH Funaate »FADH; FAD a- Ketoglutarate Succinate NAD ATP Succinyt CuA NADH ADP - P, If you were told to add one of the eight citric acid cycle intermediates to the culture medium fo yeast growing in the laboratory, what do you think would happen to the rates of ATP and carbon dioxide production? (see the above figure) a. There would be no change in ATP production, but the rate of CO2 production would increase. b. The rates of ATP production and CO2 production would both increase, c. The rate of ATP production would increase, but the rate of CO2 production would decrease. d. The rates fo ATP and CO2 production would both decrease.
In step 7 of the citric acid cycle, fumarase catalyzes the addition of a water molecule to a carbon–carbon double bond (see Panel 13¬–2). Can this be considered an oxidation reaction? Explain your answer.
There are eight chemical reactions that occur in the citric acid cycle process. The reactions of the citric acid cycle are shown in the figure below. acetyl-coenzyme A 0 CH₂-C-CoA HO-CH Reaction 7 O malate CH₂ CH || CH fumarate FADH₂ Reaction 6 FAD H+ + NADH NAD+ 1,0 H₂C CH₂ CH₂ Reaction 8 succinate ADP 0=C GTP CH₂ oxaloacetate Reaction 5 H-COA GDP ATP H₂O Reaction 1 C Reactions of the Citric Acid Cycle CH₂ CH₂ H-COA 0=C 1 CoA succinyl-CoA H+ HO-C Reaction CO₂ с CH₂ NADH CH₂ citrate Reaction 2 H-COA Reaction 3 CO₂ I CH₂ T CH₂ 0=C NAD+ HO–CH a-ketoglutarate CH, CH isocitrate NAD+ H+ + NADH In chapters 9 and 10, you were introduced to several classes of organic reactions. These classes include esterification, decarboxylation, hydration reactions, dehydration of alcohols, oxidation of alcohols, oxidation of aldehydes, reduction of aldehydes, and reduction of ketones. Find at least one of these reaction classes in the citric acid cycle. List the reaction number and the reaction. Write a…
1. The citric acid cycle ends with the reaction catalyzed by malate dehydrogenase (MDH) shown below. The product of this reaction, oxaloacetate (OAA), combines with acetylCoA (catalyzed by citrate synthase) to begin the cycle. Given this answer the following questions. All of your work must be shown. R = 8.314 J mol-1 K -1 Malate + NAD* OAA + NADH a. What is the keq of the reaction given that AG" = 30.0 kJ/mol? Assume T = 298K. Please show your work. b. The concentration of malate within a rat mitochondria is about 0.20mM. Furthermore, the ratio of [NAD+]/[NADH] is around 10/1. Given this calculate the concentration of OAA within the mitochondria considering that the MDH reaction is at equilibrium under mitochondrial conditions. c. Citrate synthase catalyzes the first step in the CAC as shown below. Determination of its actual free energy change is difficult for a number of reasons however most scientist will point to the fact that it is negative. Let's assume AG = -5.0 kJ/mol. The…
In which of the following citric acid cycle reactions does the coenzyme FAD participate? * citrate - isocitrate O succinate - fumarate O malate - oxaloacetate O more than one correct response O no correct response
Two biochemistry students are about to usemitochondria isolated from rat liver for an experiment on oxidative phosphorylation. The directions for the experiment specifyaddition of purified cytochrome c from any source to the reactionmixture. Why is the added cytochrome c needed? Why does thesource not have to be the same as that of the mitochondria?
The enzyme that catalyzes reaction below can be classified as: CoO COO NAD+ NADH + H* Но- | malate -C- H-Ć- dehydrogenase Охaloacetate Malate isomerase lyase hydrolase oxidoreductase ligase transferase
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Cyanide poisoning inhibits aerobic respiration at cytochrome c oxidase. Which of the following is NOT a result of cyanide poisoning at the cellular level? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a b с d e Oxygen is reduced to water The rate of glycolysis increases Cells are forced to switch to anaerobic respiration The electron transport chain is not completed None of the above Answered K Open in Reading View ✔Posubmit
Alcohol dehydrogenase (ADH), catalyzes a reaction where primary alcohol is converted an aldehyde using NAD* ADH fits in which class of enzyme? hydrolases lyases transferases O oxidoreductases QUESTION 25 In the serine protease catalytic mechanism, which of the following helps stabilize the tetrahedral intermediate? O low barrier hydrogen bond oxyanion hole aspartate side chain O histidine side chain QUESTION 26 In the catalytic mechanism of an aminotransferase, one substrate binds and reacts, leaving behind an amine group Click Save and Submit to save and submit. Click Save All Answers to save all answers. 78 Mostly dly 3 Type here to search
The Citric Acid Cycle results in (Choose all that apply) net oxidation of acetyl CoA carbons to two CO2 O three NAD to NADH reductions involving 6 electrons one FADH2 to FAD oxidation involving 2 electrons three NADH to NAD oxidations involving 6 electrons O one FAD to FADH, reduction involving 2 electrons O a substrate level phosphorylation