There are two stereoisomers of 1-tert-butyl-4-chloro-cyclohexane. One of these isomers reacts with sodium ethoxide in an E2 reaction that is 500 times faster than the reaction of the other isomer. Identify the isomer that reacts faster and explain the difference in rate for these two isomers.
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Q: The cis isomer of 1-bromo-4-tert-butylcyclohexane undergoes E2 elimination about 1,000 times faster…
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- Write out the mechanism (intermediate/transition state) for this reaction; Br CH3 NaOCH₂ E₂Acetic anhydride reacts with water in the following manner: CH3C(O)-O-C(O)CH3 + H2O = 2CH3CO2 If this reaction is carried out in an inert solvent with low concentrations of both acetic anhydride and water, it follows the rate law rate = k [CH3C(O)-O-C(O)CH3] [H2O] with a rate constant of 0.0035 s-1. However, if low concentrations of acetic anhydride are placed in pure water, it follows the rate law rate = K [CH3C(O)-O-C(O)CH3] where K = 0.1944 s-1. Explain why this is happening.Choose which class of pericyclic reactions the following reaction belongs to, and use the number of electron pairs involved in the reaction and the product's stereochemistry to ascertain whether the reaction proceeds thermally or photochemically. H CH3 CH3 CH₂ CH3 CH₂ CH3 Check all that apply. cycloaddition sigmatropic rearrangement ene reaction electrocyclic reaction thermal conditions photochemical conditions
- 3-Chloro-1-butene reacts with sodium ethoxide in ethanol to produce 3-ethoxy-1- butene. The reaction is second order, first order in 3-chloro-1-butene, and first order in sodium ethoxide. In the absence of sodium ethoxide, 3-chloro-1-butene reacts with ethanol to produce both 3-ethoxy-1-butene and 1-ethoxy-2-butene. Explain these results.The reaction of bromomethane with azide ion (N3-) in methanol is a typical SN2 reaction. What happens to the rate of the reaction if [N3-] is doubled?5c) Write the rate equation for the following SN1 reaction:
- When the alkyl bromides (listed here) were subjected to hydrolysis in a mixture of ethanol and water (80% EtOH/20% H2O) at 55 °C, the rates of the reaction showed the following order: (CH3)3CBR > CH3Br > CH3CH2Br > (CH3)2CHBR Provide an explanation for this order of reactivity.Chloromethane reacts with dilute sodium cyanide (Na+ -C‚N) chloromethane cyanide acetonitrile chloride. When the concentration of chloromethane is doubled, the rate is observed to double. When the concentration of cyanide ion is tripled, the rate is observed to triple. Write the rate equation for this reaction.methanol + CH3OH Suppose you were told that the above reaction was a substitution reaction but you were not told the mechanism. Evaluate the following categories to determine the reaction mechanism and then draw the structure of the major organic product. Type of alkyl halide: Type of nucleophile: Solvent: Is the product racemic?
- Formulate the reaction. Explain the stereochemistry of the products based on the mechanism of the reactions. H2SO4 Et!! Me 'Et ELOH H(1R,2R)-1-Bromo-2-methylcyclopentane is reacted with sodium methoxide. Given the product(s) and show the reaction mechanism, including the depiction of the transition state. Draw an energy diagram for this conversion.The mechanism that allows the exothermic hydrolysis of t-butyl chloride to form t-butyl alcohol and chloride ion is as follows: (CH3)3CCl → (CH3)3C+ + Cl− (CH3)3C+ + H2O → (CH3)3COH + H+ Draw the transition state for each step.