NOTE: Your only sources of carbon in the final product are the starting materials on the left. It is acceptable to have other carbon sources in reagents and protecting groups. You may assume that you have the starting materials in separate bottles and can react them separately. NOTE: Remember, you can define R groups. -CEN OH Compound R
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- Give a clear handwritten answer..complete the following reaction with missing reagentsBiaryls, compounds containing two aromatic rings joined by a C–C bond, can often be efficiently made by two different Suzuki couplings; that is, either aromatic ring can be used to form the organoborane needed for coupling. In some cases, however, only one route is possible. With this in mind, synthesize each of the following biaryls using benzene as the starting material for each aromatic ring. When more than one route is possible, draw both of them. You may use any required organic or inorganic reagents.A) Provide a reasonable multistep synthesis of the following molecule from the indicated starting material, using any reagents necessary. Please include both a retrosynthesis and a forward synthesis (that includes the product and reagents of each individual step in your synthesis). B) If you started with 1 mole of starting material and each step of your synthesis gave 100% yield, how many moles of the product drawn would you end with?
- Bringing together your knowledge of the reaction chemistry of substituted benzenes, suggest a preparative route for conversion of compound A to compound B shown below [Hint: this will take several sequential reaction steps and will involve different reactionsProvide the appropriate reagent(s) for the following transformationCome up with a synthetic route to achieve the following transformation.
- Propose a sequence of reactions to prepare the specified target compound from the indicated starting materials. All of the carbon atoms in the target must originate in the specified starting materials. Keeping this restriction in mind, you may use any other organic or inorganic reagents necessary to complete the synthesis. It is only necessary to show the overall transformations involved in your proposed synthesis.Provide a reasonable multistep synthesis of the following molecule from the indicated starting material, using any reagents necessary. Please include both a retrosynthesis and a forward synthesis (that includes the product and reagents of each individual step in your synthesis).(a) What reagents would be used for the conversion of alkene A into the target? (b) What reaction is involved in the conversion of alcohol B into alkene A? Suggest a reagent that might affect this transformation. (c) Give a retrosynthetic analysis showing the disconnection of B, the synthons produced that lead to the synthetic equivalents given (draw their structures).
- Propose a synthesis of molecule B from molecule A. For each step, indicate the necessary reagents.Write the products for (A-I). Label products with the mechanism (Sn2, Sn1, E1, E2) that produced it and write out and label major vs minor elimination products.Devise a synthesis for this product by using no larger than two or three carbons, or benzene as your only organic source of carbon.