Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder that affects the normal function of red blood cells and can eventually lead to anemia. The trait is controlled by a recessive allele found on the X chromosome. An affected son was born to a man and woman who were unaffected. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotypes of the affected boy’s parents. c. Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder that affects the normal function of red blood cells and can eventually lead to anemia. The trait is controlled by a recessive allele found on the X chromosome. An affected son was born to a man and woman who were unaffected. The woman’s mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotypes of the affected boy’s parents. c. Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder that affects the normal function
of red blood cells and can eventually lead to anemia. The trait is controlled by a recessive allele found on
the X chromosome. An affected son was born to a man and woman who were unaffected. The woman’s
mother was affected while the father was normal.
a. Indicate the gene notation.
b. Give the genotypes of the affected boy’s parents.
c. Derive the genotypic and
d. What is the probability that they will have a phenotypically normal daughter as their first child?
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