Consider the production of lauric acid (12:0) in the fruit of a coconut tree. The source of the carbon is glucose that has been produced in other parts of the plant (a) How many molecules of glucose are needed to produce the acetyl CoA for one molecule of lauric acid? (b) How many NADH are produced in the conversion of glucose to acetyl CoA? (c) Let's assume that the NADH is converted to NADPH. Is there sufficient NADPH for synthesis of lauric acid? If yes, what amount of NADH is left over? If no, what amount of NADPH must be supplied by another pathway? (d) How many ATP are produced in the conversion of glucose to acetyl CoA? (e) The acetyl CoA is produced in the mitochondria and must be transported to the cytosol. Is there sufficient ATP for synthesis of lauric acid? If yes, what amount of ATP is left over? If no, what amount of ATP must be supplied by another pathway?

Consider the production of lauric acid (12:0) in the fruit of a coconut tree. The source of the carbon is glucose that has been produced in other parts of the plant (a) How many molecules of glucose are needed to produce the acetyl CoA for one molecule of lauric acid? (b) How many NADH are produced in the conversion of glucose to acetyl CoA? (c) Let's assume that the NADH is converted to NADPH. Is there sufficient NADPH for synthesis of lauric acid? If yes, what amount of NADH is left over? If no, what amount of NADPH must be supplied by another pathway? (d) How many ATP are produced in the conversion of glucose to acetyl CoA? (e) The acetyl CoA is produced in the mitochondria and must be transported to the cytosol. Is there sufficient ATP for synthesis of lauric acid? If yes, what amount of ATP is left over? If no, what amount of ATP must be supplied by another pathway?

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

See similar textbooks

Similar questions

Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.
In the first step of the TCA cycle the acetyl group of acetyl-CoA is transferred to oxaloacetate to produce citrate. Where will the carbonyl carbon of that acetyl group be after the first CO2 is expelled? Group of answer choices The first carbon of α-ketoglutarate The last carbon of α-ketoglutarate The fourth carbon of α-ketoglutarate The third carbon of α-ketoglutarate
How many molecules of acetyl CoA, FADH2, and NADH are produced in the catabolism of a molecule of arachidonic acid, an 20-carbon carboxylic acid? How many times does the spiral reaction sequence occur
If oxidation of acetyl-CoA yields 10 ATPs per mole through the citric acid cycle, how many ATPs will be derived from the complete metabolic oxidation of 1 mole of alanine in a mammal? Would the corresponding energy yield in a fish be higher or lower? Why? How much energy would be derived from the metabolic oxidation of 1 mole of isoleucine to CO2, H2O, and NH3? Of tyrosine?
Explain Why Synthesizing Glucose from Pyruvate in the Anabolic Process of Gluconeogenesis requires more energy than is captured during the Catabolic Process of Oxidizing Glucose (through glycolysis) to Pyruvate - How much of the energy (what percentage) of oxidizing Glucose to Pyruvate is captured in Catabolism as NADH (+ H+) and ATP ? - What happens to the rest of the energy of oxidizing Glucose to Pyruvate? How much energy (what percentage) is needed to synthesize Glucose from Pyruvate?
If the carbonyl carbon of acetyl-CoA were marked with 14C, where would that carbon be located within oxaloacetate after one turn of the TCA cycle?
Complete the following description of the mechanism of the pyruvate dehydrogenase complex by using words provided. Not all words will be used. Each word will be used only one time. Three enzymes of the pyruvate dehydrogenase complex work together to catalyze the production of Acetyl CoA from Pyruvate. First, a 2-carbon unit composed of Carbons # ____ and ____ of Pyruvate are added to the co-enzyme ______ and whereas Carbon # ______ leaves as CO. The C-2 unit together with the co-enzyme is called ______ .The C-2 unit is then transferred to the 2nd co-enzyme ____, which is initially in it ___ state. The enzyme that catalyzes this step is ______.From here, the C-2 unit is transferred to form a _____ linkage with CoA-SH to generate_____
Complete the following description of the mechanism of the pyruvate dehydrogenase complex by using words provided. Not all words will be used. Each word will be used only one time. 5 Three enzymes of the pyruvate dehydrogenase complex work together to catalyze the production of Acetyl CoA from Pyruvate. First, a 2-carbon unit composed of Carbons # Pyruvate are added to the co-enzyme and whereas Carbon # of leaves as CO» The C-2 unit together with the co-enzyme is called transferred to the 2nd co-enzyme 11 12 The C-2 unit is then which is initially in its state. The enzyme that catalyzes this step is From here, the C-2 unit is transferred to form a linkage with CoA-SH to generate Acetyl COA Oxidized Hydroxyethyl TPP Phosphodiester Reduced Hydroxypropiony! TPP Lipoamide E-1 NADH 3 Dihydrolipoyl dehydrogenase Thioester 2 HydroxyacetyITPp Dihydropipoyl Transacetylase Type the words in the correct order separated by commas. Example: 1, 3, E-1, Thioester, Lipoamide ...
One consequence of ethanol addiction is fatty liver disease, an illness in which liver cells accumulate large amounts of triacylglycerols, the esters derived from glycerol and fatty acids. Ethanol is oxidized in the cytoplasm of liver cells by alcohol dehydrogenase and aldehyde dehydrogenase to yield acetate and 2 NADH. Acetate is then transported into the mitochondrion, where it is converted to acetyl-CoA and metabolized in the citric acid cycle. When alcohol is consumed in excessive quantities, the resulting high levels of NADH cause metabolic abnormalities, one of which is high levels of fatty acid synthesis. Fatty acid synthesis, also a cytoplasmic process, uses acetyl-CoA as a substrate and NADPH as a reducing agent. Speculate about how a high level of cytoplasmic NADH provides a source of NADPH for fatty acid synthesis.
What are the direct products of b oxidation of a fully saturated, straight-chain acyl-CoA of 13 carbons? How many ATP molecules can be obtained from complete oxidation of this compound?
Write the chemical equation for the conversion of 4 moles of glucose to pyruvate via glycolytic pathway
Give the number of the following:a. number of acetyl-CoA that enters the TCA cycle for every 5 molecules of glucoseb. number of high-energy phosphate groups required for the complete formation of glucose during gluconeogenesisc. number of NADPH produced for each molecule of glucose in the pentose phosphate pathway