ANSWERS TO QUESTIONS ON LABORATORY ASSAY NO.6 1. Give the importance of Rh Typing 2. List the major Rh antigens from most immunogenic to the least immunogenic? 3. Give some causes of false positive and false negative reactions.
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- 1. What is Du? ANSWERS TO QUESTIONS ON LABORATORY ASSAY NO.7 2. Why do we need test for Du when weak or no reaction is obtained in Rh typing? 3. What is required to demonstrate the presence of cells carrying a weak D antigen? 4. Explain the mechanism behind the existence of Dº. 5. Cite possible situations in which an attending physician would request for an emergency screening for the presence of "D" antigen.1. What is Du? ANSWERS TO QUESTIONS ON LABORATORY ASSAY NO.7 2. Why do we need test for Du when weak or no reaction is obtained in Rh typing? 3. What is required to demonstrate the presence of cells carrying a weak D antigen? 4. Explain the mechanism behind the existence of Du. 5. Cite possible situations in which an attending physician would request for an emergency screening for the presence of "D" antigen.1. What is the purpose of Rh view bow? What is the optimum temperature for detection of Rh antigen? 2. Give the different types of Rh antigen typing reagents accdg. to the sources. Explain each.
- 1. What is an antiserum? 2. What are the potency requirements in an antiserum? ANSWERS TO QUESTIONS ON LABORATORY ASSAY NO.4 3. What kind of antigen will anti-A detect? Anti-B? 4. Enumerate the common causes of false positive and false negative result in ABO forward grouping? 5. Give the purpose of Blood typing. 6. Cite the biochemical components of the ABO blood group accordingly. 7. Complete the table below Blood type A B 0 AB (positive/pos) for agglutination (negative/neg) for no agglutination Anti-A Anti-B1. Give the advantages of using tube method over the slide method. Why do you have to incubate the tube method in Rh typing? 2. Give the clinical importance of determining the Rh status of a patient? 3. Define HDN and explain the effect of Rh(D) antigen. What is the preventive measure of preventing D-negative mothers from forming anti-D? 4. What are the symptoms in Rh-mediated hemolytic transfusion reactions?Materials and Methods Effect of Altitude on Hematocrit and Hemoglobin Concentration 1. Dependent Variable: Hct and Hb 2. Independent Variable: altitude 3. Controlled Variables: gender, age ABO and Rh Typing in Family Members 1. Dependent Variable: presence or absence of agglutination 2. Independent Variable: type of antigen on RBCS 3. Controlled Variables: no controlled variables 4. When exercising subjects move from low to high altitude, Hct will: 5. When exercising subjects move from low to high altitude, Hb will: 6. Agglutination will occur: Results Table 3: Effect of Altitude on Hct and Hb Low Altitude High Altitude Hb Hb Length of Whole Blood Column Length of Packed RBC Column (mm) (g/100 ml Length of Whole Blood Column (mm) Length of Packed RBC Column (mm) (g/100 ml Hematocrit Hematocrit (mm) (%) blood) (%) blood) Subject 50 23 46 14.5 49 25 51 17.4 Subject 50 21 42 14.5 50 23 46 17.4 Subject 51 22 43 14.5 49 25 51 17.4 Average 50 22 44 14.5 49 24 49 17.4 Changes in Blood…
- Briefly explain the significance of RH factor. Why mother with Rh negative blood should receive RhoGAM shot? What type of antibodies would be produced in this case? Why there is no universal donor anymore? What type of blood you can transfuse if patient has type A- blood?Discuss in detail the role of CTLA-4 and PD-1/PD-L1; compare and contrast the two pathways in immunotherapy. Do the two pathways play a complementary and/or synergistic roles? Give an example of 1 approved drug for each pathway along with information on immunogenicity, route of administration, dosing regimen, and key PK parameters such as half-life and clearance.Presents the topic and objectives of SARSand include itsimplications to the human body as well as the actions of the body s immune response.
- O antibodies. Question 6 Your patient is experiencing peripheral edema because of inflammation. A) Name the four signs of inflammation. B) Which capillary pressure would change AND which direction would you expect fluid to flow (in capillary OR out of capillary)? Edit View Insert Format Tools Table 12pt Paragraph v BIU. Question 7 11 Does a vaccine cause a B cell or T cell response and why? T² : V 0 words 10 pts 10 4) 11:37 A 12/16/2Question:- Compare and contrast different vaccines that use whole-microbe approaches. Compare and contrast different vaccines that use whole-microbe approaches versus subunit or genetic approaches. What are the similarities and differences… between vaccine-induced and infection-induced herd immunity.Please answer all questions 1. What can mutation lead trastuzumab resistance with lapatinib sensitivy from HER2+ cancers. 2. What can another oncogeneic mutation be which lets HER2+ tumors being positive, have resistance to the lapatanib.