a) The allele frequency of albinism is 0.12 in a population of 450 individuals. If the number of individuals that are carriers of albinism is 101. Calculate the number of individuals with normal pigmentation? b) A rare disease which is due to a recessive allele (A) that is lethal when homozygous occurs within a specific population at a frequency of three in a million. How many individuals in a town with a population of 3000 will be expected to carry this allele?
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
a) The allele frequency of albinism is 0.12 in a population of 450 individuals. If the number of individuals that are carriers of albinism is 101. Calculate the number of individuals with normal pigmentation?
b) A rare disease which is due to a recessive allele (A) that is lethal when homozygous occurs within a specific population at a frequency of three in a million. How many individuals in a town with a population of 3000 will be expected to carry this allele?
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