In the genetics unit you learned that sickle cell anemia is an autosomal recessive condition.  In 2016, assume in the City of Markham there are 1000 people out of 300000 people who have sickle cell anemia.  Assume global warming continues for the next 50 years and in the year 2066 there are 20000 people out of 500000 in Markham who have sickle cell anemia.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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  1. In the genetics unit you learned that sickle cell anemia is an autosomal recessive condition.  In 2016, assume in the City of Markham there are 1000 people out of 300000 people who have sickle cell anemia.  Assume global warming continues for the next 50 years and in the year 2066 there are 20000 people out of 500000 in Markham who have sickle cell anemia.                                                                                                        a)What are the allele frequencies in 2016?  What are the allele frequencies in 2066? Is microevolution evident?                                                                                                                                                       b)Due to global warming, assume the numbers of malaria carrying mosquitoes in Markham dramatically increased between 2016 and 2066.  What do you believe is the main cause of the microevolution in Markham?  (Hint- refer to the 5 factors affecting microevolution and refer back to notes you took on sickle cell anemia.                                                                                                                                                               c) In 2066 what number of people do you expect to be heterozygous?  Show your calculations.                         d) If two heterozygous people get married what is the probability that their first child will have sickle-cell anemia?
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