Sucrose is a disaccharide that is hydrolyzed to glucose and fructose. Let's consider the complete oxidation in the skeletal muscle of the resulting glucose and fructose from one molecule of sucrose. It is strongly suggested that you use a table to keep track of the metabolic pathways involved as this is the best way to show the full work that is required. a) If both glucose and fructose are substrates for hexokinase, how many NADH, FADH2, and ATP (from substrate level phosphorylations) are produced during the complete oxidation to CO₂? b) If the resulting NADH and FADH2 enter electron transport, how many protons are pumped into the intermembrane space? Keep in mind that this is occurring in skeletal muscle. c) What is the maximum yield of ATP from the complete oxidation of sucrose in the muscle? Don't forget to add any ATP from substrate level phosphorylations.
Sucrose is a disaccharide that is hydrolyzed to glucose and fructose. Let's consider the complete oxidation in the skeletal muscle of the resulting glucose and fructose from one molecule of sucrose. It is strongly suggested that you use a table to keep track of the metabolic pathways involved as this is the best way to show the full work that is required. a) If both glucose and fructose are substrates for hexokinase, how many NADH, FADH2, and ATP (from substrate level phosphorylations) are produced during the complete oxidation to CO₂? b) If the resulting NADH and FADH2 enter electron transport, how many protons are pumped into the intermembrane space? Keep in mind that this is occurring in skeletal muscle. c) What is the maximum yield of ATP from the complete oxidation of sucrose in the muscle? Don't forget to add any ATP from substrate level phosphorylations.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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