Kennedy’s Disease is an Incurable Neuromuscular Disorder. What is Kennedy’s Disease? Kennedy’s disease is an inherited neurodegenerative disorder that affects both the spinal and bulbar neurons. KD is a lower motor neuron disorder because it interrupts the transmission of nerve cell signals in the brain and spinal cord. This interruption affects the spinal and bulbar neurons causing the major symptoms muscle atrophy, weakness, contraction fasciulations, and bulbar weakness. KD is the first of the
Title: A Case Report of Suspected Malignant Hyperthermia where Patient Survived the Episode. Abstract; Malignant hyperthermia is rare inherited disorder in our part of world, there are only few cases reported in literature in India who were suspected of having this condition. Overall incidence of malignant hyperthermia during general anesthesia is estimated to range from 1: 5,000 to 1: 50,000-100,000 and mortality rate is estimated to be less than 5% in presence of standard care. In India
Creatine (Cr) is a popular dietary supplement used by athletes to increase sports performance, muscle mass, and strength. Creatine was first discovered in “1835, when a French scientist reported finding this constituent of meat” (Demant & Rhodes, 1999). This organic compound is manufactured endogenously by the liver and kidneys “from the amino acids glycine, arginine and methionine” for energy stipulation during muscular contraction. (Arazi, Rahmaninia, Hoseini, & Asadi, 2011). Creatine is either
33% of patients suffering from this skeletal muscle syndrome (Torres et. al, 2015). Skeletal muscle tissues release toxins that can cause buildup within the kidneys. The large amount of toxins that were accumulated within the kidneys are serum creatine kinase, creatinine, potassium, and calcium as well as myoglobin (Chatzizisis et. al, 2008). The accumulation of myoglobin is nephrotoxic to the kidneys. Hypovolemia is another factor that leads to renal hypo perfusion (Chatzizisis et. al, 2008). Baywater
high force eccentric exercise. They found that the stretch-shortening cycle(SSC) what occurs during a drop jump, causes muscle damage in the muscle and therefore contributes to DOMS and is similar to the damage done by running. The appearance of Creatine Kinase in the blood following exercise has been used as an indirect measure of muscle damage and a study by Clarkson & Hubal (2002) looked into various different markers of muscle damage in the blood and CK was investigated compared to other blood markers
that ischemic heart disease is considered the world 's biggest killer1, it is imperative to investigate such patients at length to exclude coronary artery disease (CAD). Physicians commonly rely on the measurement of cardiac biomarkers such as creatine kinase (CK) and its isoenzymes for such a differential diagnosis. Despite the determination of Troponin levels in the evaluation of myocardial ischemia, an elevated CK-MB can provide diagnostic uncertainty as it rises earlier than troponin in myocardial
The affects of Duchenne muscular dystrophy as well as various solutions performed to provide accurate diagnoses and treatment of Duchenne muscular dystrophy. 1. Introduction Duchenne muscular dystrophy (DMD) is defined as a chronic form of dystrophy that is caused by a mutated gene. This essay critically discusses Duchenne muscular dystrophy as a whole, including all the symptoms, causes as well as treatment. 2. Overview of Duchenne muscular dystrophy Duchenne muscular dystrophy was discovered
Possible explanations for differences between our findings and other published data could be attributed to age, exercise protocol and intensity of exercise. Serum creatine kinase (CK) and lactate dehydrogenase (LDH) are an indication of the degree of metabolic adaptation to physical training of skeletal muscles. These enzymes are involved in muscle metabolism, and their serum concentration is normally very low. They increase
Article Critiques Assignment Six Hall, A. H., Leveritt, M. D., Ahuja, K. D., & Shing, C. M. (2013). Coingestion of carbohydrate and protein during training reduces training stress and enhances subsequent exercise performance. Applied Physiology, Nutrition & Metabolism, 38(6), 597-604. Despite extensive research on the benefits of carbohydrate (CHO) ingestion improving endurance performance, there are still a lot of questions in the literature about whether or not the simultaneous ingestion of CHO
symptom. The diagnosis for IBM, although difficult, simply because the symptoms may be caused by other illnesses, is based on clinical signs and subsequent testing. Many tests can help diagnose the disease , including a blood test that screens for creatine kinase or CK levels. The result of muscle cell damage is the blood enzyme CK. High CK levels would then show strange muscle damage. An electromyography, which is a technique for recording the electrical activity of muscles, can be used to recognize