Interpretation:
- The strong acid has to be predicted.
Concept Introduction:
Electronic effect:
Electron donating groups decreases acidity by inductive effect (withdrawal of electrons through a sigma bond). Electron withdrawal increases acidity. Electron-donating substituents destabilize a base, and decrease the strength of its conjugate acid; electron-withdrawing substituents stabilize a base, which increase the strength of its conjugate base.
Effect of delocalized electrons on
Due to Inductive effect, an anion is stabilized by a nearby electronegative atom. In the same way, electron delocalization also effective on stabilization of anion.
Rule: The strength of an acid depends on the stability of its conjugate base.
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Organic Chemistry, Books a la Carte Edition (8th Edition)
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