Biology: The Unity and Diversity of Life (MindTap Course List)
Biology: The Unity and Diversity of Life (MindTap Course List)
15th Edition
ISBN: 9781337408332
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 8, Problem 2CT

Review Figures 8.12 and 8.13. In cells, the primers for DNA synthesis are short strands of RNA, so each newly-synthesized strand of DNA has a segment of RNA al its 5′ end. As replication proceeds, DNA polymerases remove these RNA segments and fill in the resulting gaps with DNA. However, the gaps at the very 5′ ends of the new strands cannot be filled in with DNA. Why not? DNA replication leaves exposed about 100 nucleotides al the 5′ end of each template strand, and these single-stranded ends are removed. What are the effects of this "end problem" on a cell's DNA as it continues to divide?

Chapter 8, Problem 2CT, Review Figures 8.12 and 8.13. In cells, the primers for DNA synthesis are short strands of RNA, so , example  1

FIGURE 8.12 DNA replication.

Green arrows show the direction of synthesis for each strand. The Y-shaped structure where the DNA molecule is being unwound is called a replication fork.

Chapter 8, Problem 2CT, Review Figures 8.12 and 8.13. In cells, the primers for DNA synthesis are short strands of RNA, so , example  2

Chapter 8, Problem 2CT, Review Figures 8.12 and 8.13. In cells, the primers for DNA synthesis are short strands of RNA, so , example  3

FIGURE 8.13 Discontinuous synthesis of DNA.

This close-up of a replication fork shows that only one of the two new DNA strands is assembled continuously. The other is assembled in short segments.

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Review Figures 8.12 and 8.13. In cells, the primers forDNA synthesis are short strands of RNA, so each newlysynthesized strand of DNA has a segment of RNA atits 5′ end. As replication proceeds, DNA polymerasesremove these RNA segments and fill in the resulting gapswith DNA. However, the gaps at the very 5′ ends of thenew strands cannot be filled in with DNA. Why not?DNA replication leaves exposed about 100 nucleotidesat the 5′ end of each template strand, and these singlestranded ends are removed. What are the effects of this“end problem” on a cell’s DNA as it continues to divide
(a) What is the function of helicase in DNA replication?(b) What is the function of DNA polymerase?(c) What are replication forks? Compare and contrast leading and lagging strands. Answer all please
(a) Eukaryotic DNA replication is more complex than prokaryotic replication. Give one reason why this should be so. (b) Why might eukaryotic cells need more kinds of DNA polymerases than bacteria?

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