Concept explainers
To define: The effects of the tripolar and tetrapolar spindle on resulting nuclei.
Introduction: The tripolar and tetrapolar spindle are formed in unregulated cell divisions. These are very common in infected cells, where cells do not have proper checkpoints.
To describe: Whether the cells resulting from multicellular mitosis have any chromosomal imbalances.
Introduction: The anticancer drugs prevent the shortening of chromosomes before binding to the microtubules. On preventing condensation of chromosomes, mitotic division fails in the cancerous cells.
To describe: The expectations of reduction in cell survival resulting from chromosomal imbalances.
Introduction: Chromosomal imbalance results in tumor initiation. Chromosomal imbalances sometimes affect the gene activity that suppresses the cell division.
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