Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 7, Problem 2PDQ

Review the Chapter Concepts list on p. 151. These all center around sex determination or the expression of genes encoded on sex chromosomes. Write a short essay that discusses sex chromosomes as they contrast with autosomes.

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Mitotic nondisjunction can occur, particularly in tumor cells. Assume a single nondisjunction event involving the X chromosome occurs in a cell undergoing mitosis in a human female. First, consider the daughter cell with the smaller number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?    Next, consider the daughter cell with the larger number of chromosomes: How many total chromosomes will this cell have?  How many X chromosomes will this cell have?
With regard to the numbers of sex chromosomes, explain whydosage compensation is necessary
Explain why nondisjunction of sex chromosomes is more well-tolerated thannondisjunction in autosomes, even though genetic nondisjunction of sex chromosomes usually results in sterility and abnormalities of sex organs.

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Concepts of Genetics (12th Edition)

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