BROOKER BIOLOGY
BROOKER BIOLOGY
5th Edition
ISBN: 9781307656152
Author: BROOKER
Publisher: MCG/CREATE
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Chapter 5.1, Problem 1CS

Core Skill: Modeling The goal of this modeling challenge is to propose a model for a transmembrane protein.

Modeling Challenge: As shown in Figure 5.2, some α helices, which are called transmembrane a helices, may be inserted into the hydrophobic region of a membrane and span the entire membrane. Let’s suppose a protein in the plasma membrane has 5 transmembrane α helices. The loops that connect these 5 transmembrane segments are relatively short, except for the one that connects transmembrane segments 4 and 5, which is longer. The amino end projects into the cytosol. Draw a model of this transmembrane protein in the plasma membrane. In your model, draw the transmembrane a helices as cylinders and label them 1 through 5. Also label the amino and carboxyl ends and the cytosol and extracellular environment.

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Choices for 1: hydrophobic or hydrophilicChoices for 2: hydrophobic or hydrophilic Choices for 3: on the surface or in the coreChoices for 4: on the surface or in the core
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Is there more than one subunit shown? Is your protein bound to anything else? Describe the secondary structures you see.
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