Statistics: The Art and Science of Learning from Data (4th Edition)
4th Edition
ISBN: 9780321997838
Author: Alan Agresti, Christine A. Franklin, Bernhard Klingenberg
Publisher: PEARSON
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Chapter 5, Problem 88CP
Screening for heart attacks Biochemical markers are used by emergency room physicians to aid in diagnosing patients who have suffered acute myocardial infarction (AMI), or what’s commonly referred to as a heart attack. One type of biochemical marker used is creatine kinase (CK). Based on a review of published studies on the effectiveness of these markers (by E. M. Balk et al., Annals of Emergency Medicine, vol. 37, pp. 478–494, 2001), CK had an estimated sensitivity of 37% and specificity of 87%. Consider a population having a prevalence rate of 25%.
- a. Explain in context what is meant by the sensitivity equaling 37%.
- b. Explain in context what is meant by the specificity equaling 87%.
- c. Construct a tree diagram for this diagnostic test. Label the branches with the appropriate
probabilities.
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Students have asked these similar questions
Anemia (low healthy blood cells or hemoglobin) has an important role in exercise performance.
However, the direct link between rapid changes of hemoglobin and exercise performance is
still unknown. A study investigated 18 patients with a blood disorder (beta-thalassemia).
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transfusion. Data are given in the table.
HB = Hemoglobin
RER = Respiratory exchange
ID
Change in
HB
Obese
RER > 1.1
ratio
No
No
1
-1.4
No
-1.5
No
Yes
No
Yes
3
-2
No
4
-2.1
No
-1.9
Yes
Yes
No
-1.6
-1.8
-0.8
6
7
No
Yes
No
Yes
8
9.
-1
No
No
-1.2
No
Yes
10
11
No
No
-0.8
-1.5
12
Yes
No
No
Yes
13
14
-1.4
-2.6
-1.7
No
No
Yes
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15
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No
Yes
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16
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17
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Mental Health
A study was performed looking at the effect of physical activity on cognitive function among adults at high risk for Alzheimer's disease. There were 170 eligible subjects randomly assigned to either an exercise intervention (exercise group) or a control intervention (control group). The subjects were followed at 6-month intervals up to
18 months of follow-up. The primary assessment scale was the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). The results at 18 months of follow-up among participants with mild cognitive impairment are given in the table below. (Let population 1 be the exercise group and population 2 be the control group.
Use exercise group control group.)
Mean difference from baseline (18-month score
minus baseline score) among participants with
mild cognitive impairment in the ADAS-Cog
score*
Mean change
95% CI
n
H₁:
Exercise group Control group
USE SALT
-0.37
(-1.37, 0.63)
48
-0.43
(-1.35, 0.49)
52
(a) What is the standard deviation of…
Treating Chronic Fatigue Syndrome: Patients with chronic fatigue syndrome were tested, and then retested after being treated with fludrocortisones. Listed below are the changes in fatigue after the treatment (based on data from “The Relationship Between Neurally Mediated Hypotension and the Chronic Fatigue Syndrome” by Bou-Holaigah, Rowe, Kan, and Calkins, Journal of the American Medical Association, 274, No. 12). A standard scale from -7 to +7 was used, with positive values representing improvements. Use a 0.05 significance level to test the claim that the mean change is not zero. Does the treatment appear to be effective?
6 5 0 5 6 7 3 3 2 6 5 5 0 6 3 4 3 7 0 4 4
Hypotheses: __________________________________________________________________________________
P-value: ____________________
Conclusion on null hypothesis:
Conclusion on claim and answer to the question:
Chapter 5 Solutions
Statistics: The Art and Science of Learning from Data (4th Edition)
Ch. 5.1 - Probability Explain what is meant by the long-run...Ch. 5.1 - Testing a coin Your friend decides to flip a coin...Ch. 5.1 - Vegetarianism You randomly sample 10 people in...Ch. 5.1 - Airline accident deaths Airplane safety has been...Ch. 5.1 - World Cup 2014 The powerrank.com website...Ch. 5.1 - Random digits Consider a random number generator...Ch. 5.1 - Polls and sample size A pollster agency wants to...Ch. 5.1 - Heart transplant Before the first human heart...Ch. 5.1 - Nuclear war You are asked to use your best...Ch. 5.1 - Simulate coin flips Use the web app Random Numbers...
Ch. 5.1 - Unannounced pop quiz A teacher announces a pop...Ch. 5.2 - Student union poll Part of a student opinion poll...Ch. 5.2 - Random digit A single random digit (from 09) is...Ch. 5.2 - Pop quiz A teacher gives a four-question...Ch. 5.2 - More true-false questions Your teacher gives a...Ch. 5.2 - Rolling two dice Some friends are playing a game...Ch. 5.2 - Two girls A couple plans to have two children....Ch. 5.2 - Three children A couple plans to have three...Ch. 5.2 - Wrong sample space A couple plans to have four...Ch. 5.2 - Insurance Every year the insurance industry spends...Ch. 5.2 - Cell phone and case At the local cell phone store,...Ch. 5.2 - Seat belt use and auto accidents Based on records...Ch. 5.2 - Protecting the environment When the General Social...Ch. 5.2 - Prob. 25PBCh. 5.2 - Newspaper sales You are the director of newspaper...Ch. 5.2 - Prob. 27PBCh. 5.3 - Recidivism rates A 2014 article from Business...Ch. 5.3 - Prob. 29PBCh. 5.3 - Audit and low income Table 5.3 on audit status and...Ch. 5.3 - Religious affiliation The 2012 Statistical...Ch. 5.3 - Prob. 32PBCh. 5.3 - Prob. 33PBCh. 5.3 - Go Celtics! Larry Bird, who played pro basketball...Ch. 5.3 - Prob. 35PBCh. 5.3 - Homeland security According to an article in The...Ch. 5.3 - Down syndrome again Example 8 discussed the Triple...Ch. 5.3 - Prob. 38PBCh. 5.3 - Happiness in relationship Are people happy in...Ch. 5.3 - Prob. 40PBCh. 5.3 - Prob. 41PBCh. 5.3 - Prob. 42PBCh. 5.3 - Prob. 43PBCh. 5.3 - Prob. 44PBCh. 5.3 - Family with two children For a family with two...Ch. 5.3 - Prob. 46PBCh. 5.4 - Birthdays of presidents Of the first 44 presidents...Ch. 5.4 - Prob. 48PBCh. 5.4 - Lots of pairs Show that with 25 students, there...Ch. 5.4 - Prob. 50PBCh. 5.4 - Prob. 51PBCh. 5.4 - Prob. 52PBCh. 5.4 - Coincidence in your life State an event that has...Ch. 5.4 - Monkeys typing Shakespeare Since events of low...Ch. 5.4 - A true coincidence at DisneyWorld Wisconsin has...Ch. 5.4 - Prob. 56PBCh. 5.4 - Mammogram diagnostics Breast cancer is the most...Ch. 5.4 - Prob. 58PBCh. 5.4 - Prob. 59PBCh. 5.4 - Convicted by mistake In criminal trials (e.g.,...Ch. 5.4 - DNA evidence compelling? DNA evidence can be...Ch. 5.4 - Prob. 62PBCh. 5.4 - Simulating donations to local blood bank The...Ch. 5.4 - Probability of winning In Example 16, we estimated...Ch. 5 - Peyton Manning completions As of the end of the...Ch. 5 - Due for a boy? A couple has five children, all...Ch. 5 - Prob. 68CPCh. 5 - Choices for lunch For the set lunch at Amelias...Ch. 5 - Caught doctoring the books After the major...Ch. 5 - Life after death In a General Social Survey, in...Ch. 5 - Death penalty jury In arguing against the death...Ch. 5 - Drivers exam Three 15-year-old friends with no...Ch. 5 - Prob. 74CPCh. 5 - Health insurance According to a 2006 census bureau...Ch. 5 - Prob. 76CPCh. 5 - Prob. 77CPCh. 5 - Prob. 78CPCh. 5 - Prob. 79CPCh. 5 - Roll two more dice Refer to the previous exercise....Ch. 5 - Prob. 81CPCh. 5 - Waste dump sites A federal agency is deciding...Ch. 5 - Prob. 83CPCh. 5 - Prob. 84CPCh. 5 - Prob. 85CPCh. 5 - Death penalty and false positives For the decision...Ch. 5 - Prob. 87CPCh. 5 - Screening for heart attacks Biochemical markers...Ch. 5 - Prob. 89CPCh. 5 - Color blindness For genetic reasons, color...Ch. 5 - Prob. 91CPCh. 5 - Prostate cancer A study of the PSA blood test for...Ch. 5 - Prob. 95CPCh. 5 - Illustrate probability terms with scenarios a....Ch. 5 - Short term versus long run Short-term aberrations...Ch. 5 - Prob. 98CPCh. 5 - Mrs. Test Mrs. Test (see www.mrstest.com) sells...Ch. 5 - Prob. 100CPCh. 5 - Prob. 101CPCh. 5 - Prob. 102CPCh. 5 - Protective bomb Before the days of high security...Ch. 5 - Streak shooter Sportscaster Maria Coselli claims...Ch. 5 - Multiple choice Choose ALL correct responses. For...Ch. 5 - Prob. 106CPCh. 5 - Prob. 107CPCh. 5 - Multiple choice: Dream come true You have a dream...Ch. 5 - Prob. 109CPCh. 5 - True or false Answer true of false for each part....Ch. 5 - True or false When you flip a balanced coin twice,...Ch. 5 - Prob. 112CPCh. 5 - Prob. 113CPCh. 5 - Prob. 114CPCh. 5 - Prob. 115CPCh. 5 - Prob. 116CP
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