Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Textbook Question
Chapter 5, Problem 4A
How much ATP could be obtained from the complete oxidation of one molecule of glucose? From one molecule of butterfat containing one glycerol and three 12-carbon chains?
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Why is the isomerization of glucose-6-phosphate (G6P) to fructose-6-phosphate (F6P) an important step in glycolysis? How is the isomerization of F6P back into G6P prevented?
How many ATP are produced from a triglyceride containing three 14 carbon fatty acids?
NOTE: Assume that glycerol is converted to Glyceraldehyde-3-Phosphate (step 6 of glycolysis).
..a) Draw all of the reactions that occur in the aerobic metabolism of glucose that hydrolyze a
thiolester bond. In your answer, include complete structural formulae as well as the names of
any cofactors, enzymes, reactants and products.
b) Explain why the free energy changes that characterize these reactions are so exergonic.
Include a figure in your answer. (
c) If you were to completely catabolize 3 molecules of glucose under aerobic conditions, what
would the ATP yield be as a result of the reactions that you've drawn above?
Chapter 5 Solutions
Microbiology: An Introduction
Ch. 5 - Prob. 1RCh. 5 - DRAW ITUsing the diagrams below, show each of the...Ch. 5 - DRAW IT An enzyme and substrate are combined. The...Ch. 5 - Define oxidation-reduction, and differentiate the...Ch. 5 - There are three mechanisms for the phosphorylation...Ch. 5 - All of the energy-producing biochemical reactions...Ch. 5 - Fill in the following table with the carbon source...Ch. 5 - Write your own definition of the chemiosmotic...Ch. 5 - Why must NADH be reoxidized? How does this happen...Ch. 5 - NAME IT What nutritional type is a colorless...
Ch. 5 - Explain why, even under ideal conditions,...Ch. 5 - The following graph shows the normal rate of...Ch. 5 - Compare and contrast carbohydrate catabolism and...Ch. 5 - How much ATP could be obtained from the complete...Ch. 5 - The chemoautotroph Acidithiobacillus can obtain...Ch. 5 - Which substance in the following reaction is being...Ch. 5 - Which of the following reactions produces the most...Ch. 5 - Prob. 3MCQCh. 5 - Which of the following compounds has the greatest...Ch. 5 - Prob. 5MCQCh. 5 - Prob. 6MCQCh. 5 - Which culture produces the most lactic acid? Use...Ch. 5 - Which culture produces the most ATP? Use the...Ch. 5 - Which culture uses NAD+? Use the following choices...Ch. 5 - Which culture uses the most glucose? Use the...Ch. 5 - Haemophilus influenzae requires hemin (X factor)...Ch. 5 - The drug Hivid, also called ddC, inhibits DNA...Ch. 5 - The bacterial enzyme streptokinase is used to...
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- The complete oxidation of glucose 6-phosphate derived from free glucose yields 30 molecules ATP, whereas the complete oxidation of glucose 6- phosphate derived from glycogen yields 31 molecules of ATP. Account for this difference.arrow_forwardWhich of the selected phosphate group hydrolysis reactions listed in the table below can NOT be productively coupled to the synthesis of glucose-1-phosphate? Free energy of hydrolysis for certain phosphate bonds Compound kcal/ mol-1 Phosphoenolpyruvate -14.8 1,3-Bisphosphoglycerate -11.8 Creatine phosphate -10.3 ATP (to ADP) -7.3 Glucose 1-phosphate -5 Pyrophosphate -4.6 Glucose 6-phosphate -3.3 Glycerol 3-phosphate -2.2 ATP hydrolysis. Glucose-6-phosphate hydrolysis.arrow_forwardDuring glycolysis (under anaerobic conditions), for each glucose molecule broken down, how many ATP molecules are used and how many are made in total? A diagram summarizing the different reactions of glycolysis is given below. ATP ADP ATP ADP Glucose Glucose-6-phosphate Fructose-6-phosphate Fructose-1,6-bisphosphate Dihydroxyacetone phosphate 2 (Glyceraldehyde-3-phosphate) Glyceraldehyde- 3-phosphate 2 (1,3-Bisphosphoglycerate) 2 (3-Phosphoglycerate) 2 (2-Phosphoglycerate) 2 H₂O 2 (Phosphoenolpyruvate) 2 (Pyruvate) 2 NAD+ + 2Pi 2 NADH + 2H 2 ADP 2 ATP -2 ADP 2 ATP 2 ATP molecules are used and 2 ATP molecules are made 2 ATP molecules are used and 4 ATP molecules are made O 6 ATP molecules are used and no ATP molecules are made O 4 ATP molecules are used and 2 ATP molecules are made O No ATP molecules are used and 6 ATP molecules are madearrow_forward
- In which of the following metabolic conversions is ATP “generated” during glycolysis? Glucose —> Glucose-6-phosphate 1,3-Bisphosphoglycerate —> 3-Phosphoglycerate Fructose-1,6-bisphosphate —> Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate Glucose-6-phosphate —> Fructose-6-phosphate 2-Phosphoglycerate —> 3-Phosphoglyceratearrow_forwardWhich reaction is irreversible? oxidized glutathione + NADPH + H+ → reduced glutathione + NADP+ ribulose 5-phosphate → ribose 5-phosphate glucose 6-phosphate + NADP+ → 6-phosphoglucono-δ-lactone + NADPH + H+ sedoheptulose 7-phosphate + glyceraldehyde 6-phosphate → fructose 6-phosphate + erythrose 4-phosphate ribulose 5-phosphate → xylulose 5-phosphatearrow_forwardconsider the following fatty acid: ch3-ch2-ch2-ch2-ch2-ch2=ch-cooh. in terms of reducing equivalents, how much energy will it yield upon complete oxidation of co2? - 4 molecules of NADH and 4 molecules of FADH2 -4 molecules of NADH and 3 moleculs of FADH2 - 19 molecules of NADH and 8 molecules of FADH2 - 5 molecules of NADH and 8 molecules of FADH2 - 19 molecules of NADH and 9 molecules of FADH2arrow_forward
- Complete catabolism of one glucose molecule yields 38 ATP molecules. How many moles of ATP are produced by the complete catabolism of 10 moles of glucose?arrow_forwardWhich of the following molecules controls the metabolic flow through both glycolysis and gluconeogenesis? fructose-2,6-bisphosphate O pyruvate O 2,3-bisphosphoglycerate O Glucose-6-phosphate O lactic acid O citrate Which of the following enzymes plays a role in controlling the the half-life of CGMP? O CGMP phosphodiesterase O CGMP phosphatase O CGMP half-life controlling enzyme O CGMP kinase O CGMP phosphorylasearrow_forwardWhich of the following is the correct summary of phase II of glycolysis for each molecule of glucose? Glucose + ATP ⟶ Glyceraldehy-3-phosphate + ADP Glucose + 2 ATP ⟶ 2(Glyceraldehy-3-phosphate) + 2 ADP Glyceraldehyde-3-phosphate + NAD+ + ADP + Pi ⟶ 3-phosphoglycerate + NADH + H+ + ATP 2(3-phosphoglycerate) + 2ADP ⟶ 2 pyruvate + 2ATP 2(Glyceraldehyde-3-phosphate) + 2NAD+ + 2ADP + 2Pi ⟶ 2(3-phosphoglycerate) + 2NADH + 2H+ + 2ATParrow_forward
- Why is the sequence of reactions that catabolize fatty acids described as a spiral rather than a cycle?arrow_forwardDescribe how a) Mean Arterial Pressure, b) Maximal Oxygen Consumption, and c) Blood Flow are determined using its formula. In addition, you should explain what those factors are including cardiac output, stroke volume, heart rate, resistance, a-vO2 difference, etc. Describe how many ATPs can be generated by complete cycles of beta oxidation of free fatty acid with 20 carbons. You should indicate how many cycles of beta oxidation and Krebs cycle, and total number of products as wellarrow_forwardThe reaction pictured is an oxidation-reduction reaction in the citric acid cycle in which the energy-carrier molecule NADH is generated. Identify which molecule in the reaction will be oxidized and which molecule will be reduced. Place a single answer choice in each box. COO- HO-C-H H-C-H COO- Malate NAD+ NADH + H+ Oxidized malate oxaloacetate COO- H-C-H ī COO- Oxaloacetate Reduced NADH NAD+arrow_forward
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