Principles of Human Physiology (6th Edition)
6th Edition
ISBN: 9780134169804
Author: Cindy L. Stanfield
Publisher: PEARSON
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Textbook Question
Chapter 5, Problem 24E
Compare lipophilic and lipophobic chemical messengers with respect to the location of their receptors, their transport in blood, and their general signal transduction mechanisms.
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Describe the signal transduction pathway that lipid-soluble messengers use.
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Chapter 5 Solutions
Principles of Human Physiology (6th Edition)
Ch. 5.1 - Name the three functional classes of messengers....Ch. 5.1 - Prob. 5.1.2QCCh. 5.1 - Prob. 5.1.3QCCh. 5.2 - How does inhibiting enzymes prevent the sensation...Ch. 5.2 - What negative effects do elevated doses of aspirin...Ch. 5.2 - Prob. 3CTQCh. 5.2 - Prob. 5.2.1QCCh. 5.2 - Prob. 5.2.2QCCh. 5.2 - Prob. 5.2.3QCCh. 5.3 - Prob. 1CTQ
Ch. 5.3 - Prob. 2CTQCh. 5.3 - Prob. 3CTQCh. 5.3 - Where in the target cell are the receptors for...Ch. 5.3 - Name the three categories of membrane-bound...Ch. 5.3 - Name five substances that act as second...Ch. 5 - Prob. 1ECh. 5 -
Epinephrine is a(n)
a. Amino acid.
b....Ch. 5 - Prob. 3ECh. 5 - Prob. 4ECh. 5 - Prob. 5ECh. 5 -
Which of the following is likely to cause an...Ch. 5 -
Which of the following messenger classes bind to...Ch. 5 - Prob. 8ECh. 5 -
G proteins are involved whenever
Binding of...Ch. 5 - Prob. 10ECh. 5 - Prob. 11ECh. 5 - Prob. 12ECh. 5 - Prob. 13ECh. 5 -
When a G protein is activated, it releases a...Ch. 5 -
The enzyme that catalyzes conversion of ATP to...Ch. 5 -
Following activation of the phosphatidylinositol...Ch. 5 - Prob. 17ECh. 5 - Prob. 18ECh. 5 - Cytosolic calcium often exerts its effect by...Ch. 5 - Prob. 20ECh. 5 - Prob. 21ECh. 5 - Prob. 22ECh. 5 - Prob. 23ECh. 5 - Compare lipophilic and lipophobic chemical...Ch. 5 - Prob. 25ECh. 5 -
Describe the cAMP second messenger system,...Ch. 5 - Compare long-distance communication by the nervous...Ch. 5 -
Describe the two types of receptor- mediated...Ch. 5 - Prob. 29ECh. 5 - Prob. 30ECh. 5 - Prob. 31ECh. 5 - Prob. 32ECh. 5 - Prob. 33E
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- Distinguish among the four types of extracellular chemical messengers with regard to their source and the distance to their target cells.arrow_forwardSecond-messenger systems ultimately bring about the desired cell response by inducing a change in the shape and function of particular designated intracellular proteins. (True or false?)arrow_forwardThe class of enzyme that acts as an effector molecule to generate two lipid messengers from PIP2 is a ___________; the lipid messenger products include the membrane-bound lipid _______ and the soluble lipid messenger ________. Phospholipase; diacylglycerol (DAG); inositol 1,4,5-trisphosphate (IP3) Phospholipid kinase; diacylglycerol (DAG); inositol 1,4,5-trisphosphate (IP3) Phospholipid phosphatase; inositol 1,4,5-trisphosphate (IP3); diacylglycerol (DAG) Phospholipid kinase; inositol 1,4,5-trisphosphate (IP3); diacylglycerol (DAG)arrow_forward
- Describe the mechanisms that limit signaling by the phosphoinositide pathway.arrow_forwardList several roles of membrane receptors and that of G protein–linked receptors.arrow_forwardWhich of the following is important in signal transduction triggered by hormones?a) Phosphatidylinositol and its derivativesb) Phosphatidylserine and its derivativesc) Phosphatidylglycerol and its derivativesd) Phosphatidylethanolaminearrow_forward
- Which of the following is not associated with Perilipin? A) when phosphorylated, it re-structures fat droplets for easy degradation of triacylglycerols B) is a fat droplet-associated protein C) is phosphorylated when glucagon and epinephrine levels are high D) when phosphorylated, it helps to degrade the coactivator of ATGL Next Page Page 4 of 125arrow_forwardWhich describes the enzymatic activity/biochemical function of dynamin? Answers: bind to and (quickly) hydrolyze GTP for energy while pinching off vesicles from a donor membrane surface in collaboration with clathrin bind to signal sequences in nascent secretory proteins, the ribosome, and to the SRP receptor, bind to and (slowly) hydrolyze GTP when the ribosome is bound to the translocon bind to nuclear localization sequences and to importin-beta bind to and (slowly) hydrolyze GTP while recruiting (binding to) vesicle coat proteinsarrow_forwardOutline the three general means by which binding of a water soluble extracellular chemical messenger to its matching surface membrane receptor brings about the desired intracellular response.arrow_forward
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